View a complete listing here.
ZAP conjugates are non-targeted saporin conjugates that “piggyback” on to your primary targeting agent (biotinylated material or antibody).
Biotin-Z Internalization Kit (for in vitro or in vivo use)
These kits convert biotinylated materials into targeted toxins and will allow you to evaluate the ability of your reagent to internalize upon binding to its receptor.
| Target | Recommended Product in vivo | Recommended Product in vitro |
|---|---|---|
| biotinylated peptide | Streptavidin-ZAP Peptide Kit (KIT-27-B) | Biotin-Z Peptide Internalization Kit (KIT-27-ZB) |
| biotinylated antibody *choose host species of your material | Streptavidin-ZAP Antibody Kit (KIT-27-A) goat, human, mouse, rat, rabbit, sheep | Biotin-Z Antibody Internalization Kit (KIT-27-Z) goat, human, mouse, rat, rabbit, sheep |
| other biotinylated material | Streptavidin-ZAP Kit (KIT-27-S) | Streptavidin-ZAP Kit (KIT-27-S) |
Streptavidin-ZAP (Cat. #IT-27) converts biotinylated materials into targeted toxins.
FITC-Streptavidin-ZAP (Cat. #IT-85) eliminate cells recognized by YOUR biotinylated targeting agent, FITC-labeled
MonoBiotin-ZAP (Cat. #BT-ZAP) eliminate cells recognized by YOUR streptavidinylated targeting agent
ZAP Antibody Internalization Kit (for in vitro use)
The Antibody Z-kit contains a Secondary Antibody conjugated to Saporin (ZAP), Control Conjugate, plus all the components needed to screen your primary antibody for internalization.
| Target | Recommended Products | ||
|---|---|---|---|
| alpaca/llama IgG (VHH domain) | Alpaca-ZAP (IT-87, KIT-87) | ||
| chicken IgY | Chick-ZAP (IT-62, KIT-62) | ||
| goat IgG | Goat-ZAP (IT-36, KIT-36) | ||
| guinea pig IgG | gPIG-ZAP (IT-64, KIT-64) | ||
| human IgG | Hum-ZAP (IT-22, KIT-22) | Fab-ZAP human (IT-51, KIT-51) | FabFc-ZAP human (IT-65, KIT-65) |
| human IgM | Hug-M-ZAP (IT-43, KIT-43) | FabFc-ZAP Hug-M (IT-78, KIT-78) | |
| mouse IgG | Mab-ZAP (IT-04, KIT-04) | Fab-ZAP mouse (IT-48, KIT-48) | FabFc-ZAP mouse (IT-89, KIT-89) |
| mouse IgM | Anti-M-ZAP (IT-30, KIT-30) | ||
| rabbit IgG | Rab-ZAP (IT-05, KIT-05) | Fab-ZAP rabbit (IT-57, KIT-57) | |
| rat IgG | Rat-ZAP (IT-26, KIT-26) | Fab-ZAP rat (IT-55, KIT-55) | FabFc-ZAP rat (IT-88, KIT-88) |
 made with bivalent antibodies that recognize the whole IgG |  made with monovalent (Fab) antibodies that recognize the whole IgG, without bivalent capping |  made with monovalent (Fab) antibodies that recognize Fc region only |