Rab-ZAP [IT-05, KIT-05]

a tool to “piggyback” onto YOUR antibody via affinity-purified goat anti-rabbit IgG; targeting cells that recognize YOUR primary rabbit affinity-purified polyclonal antibody, eliminated via saporin

SKU: IT-05 Category: Antibody Type: affinity-purified | Host: Goat | Reactivity: rabbit | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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Rab-ZAP uses your primary rabbit affinity-purified polyclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-rabbit IgG) to “piggyback” onto YOUR rabbit primary antibody. Rab-ZAP can be utilized for screening rabbit IgG antibodies for internalization and/or their suitability to make potent immunotoxins.

Rab-ZAP is a chemical conjugate of affinity-purified goat anti-rabbit IgG and the ribosome-inactivating protein, saporin. It uses your rabbit affinity-purified polyclonal antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Rab-ZAP is available individually (Cat. #IT-05) or as a kit (Cat. #KIT-05) which includes Rab-ZAPSaporin (Cat. #PR-01)Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.