Recent Targeting Topics Alzheimer’s Disease modelsAward winner for animal model of temporal lobe epilepsyNew product announcements at SfN: Transfection and Epilepsy toolsSfN Poster of the Year ContendersFab-pHast products Product Catalog A TARGETING AGENT IS CONJUGATED TO A PAYLOAD. HERE THE CONJUGATE IS AN ANTIBODY LINKED TO A SMALL MOLECULE THE TARGETED CONJUGATE BINDS ONLY THE CELLS THAT ARE SPECIFIC TO THE ANTIBODY CAUSING THE RECEPTOR TO INTERNALIZE THE INTERNALIZED CONJUGATE IS DIGESTED BY ENZYMES RELEASING THE PAYLOAD INTO THE CYTOSOL. THE PAYLOAD IS THEN FREE TO ALTER THE CELL.
