Recent Targeting Topics New product announcements at SfN: Transfection and Epilepsy toolsSfN Poster of the Year ContendersFab-pHast productsOrexin-SAP Model of Sleep DisordersLeptin responsiveness in mediating weight loss Product Catalog A TARGETING AGENT IS CONJUGATED TO A PAYLOAD. HERE THE CONJUGATE IS AN ANTIBODY LINKED TO A SMALL MOLECULE THE TARGETED CONJUGATE BINDS ONLY THE CELLS THAT ARE SPECIFIC TO THE ANTIBODY CAUSING THE RECEPTOR TO INTERNALIZE THE INTERNALIZED CONJUGATE IS DIGESTED BY ENZYMES RELEASING THE PAYLOAD INTO THE CYTOSOL. THE PAYLOAD IS THEN FREE TO ALTER THE CELL.
