Goat-ZAP uses your primary goat affinity-purified polyclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified rabbit anti-goat IgG) to “piggyback” onto YOUR goat primary antibody. Goat-ZAP can be utilized for screening goat IgG antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.
Goat-ZAP uses your goat affinity-purified polyclonal antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.