FabFc-ZAP Hug-M [IT-78, KIT-78]

a tool to “piggyback” onto YOUR antibody via goat anti-human IgM monovalent antibody; targeting cells that recognize YOUR human IgM antibody, eliminated via saporin

SKU: IT-78 Category: Antibody Type: affinity-purified | Host: Goat | Reactivity: Human | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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FabFc-ZAP Hug-M uses your primary human monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. The secondary antibody used in FabFc-ZAP Hug-M will react only with the Fc portion of the IgM heavy chain. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

FabFc-ZAP Hug-M is a chemical conjugate of goat anti-human IgM antibody and the ribosome-inactivating protein, saporin. It uses your human primary IgM antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

FabFc-ZAP Hug-M is available individually (Cat. #IT-78) or as a kit (Cat. #KIT-78) which includes FabFc-ZAP Hug-MSaporin (Cat. #PR-01)Fab IgG-SAP (Cat. #IT-67) and reagents for developing a cytotoxicity assay.