Hug-M-ZAP [IT-43, KIT-43]

a tool to “piggyback” onto YOUR antibody via affinity-purified goat anti-human IgM; targeting cells that recognize YOUR primary human monoclonal IgM antibody, eliminated via saporin

SKU: IT-43 Category: Antibody Type: affinity-purified | Host: Goat | Reactivity: Human | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
Clear

Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-human IgM) to “piggyback” onto YOUR human primary antibody. Hug-M-ZAP can be utilized for screening human IgM antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

Hug-M-ZAP is a chemical conjugate of affinity-purified goat anti-human IgM and the ribosome-inactivating protein, saporin. It uses your primary human monoclonal IgM antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Hug-M-ZAP is available individually (Cat. #IT-43) or as a kit (Cat. #KIT-43) which includes Hug-M-ZAPSaporin (Cat. #PR-01)Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.