Mab-ZAP [IT-04, KIT-04]

a tool to “piggyback” onto YOUR antibody via affinity-purified goat anti-mouse IgG; targeting cells that recognize YOUR primary mouse monoclonal IgG antibody, eliminated via saporin

SKU: IT-04 Category: Antibody Type: affinity-purified | Host: Goat | Reactivity: Mouse | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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Mab-ZAP uses your primary mouse monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-mouse IgG) to “piggyback” onto YOUR mouse primary antibody. Mab-ZAP can be utilized for screening mouse IgG antibodies for internalization and/or their suitability to make potent immunotoxins.

Mab-ZAP is a chemical conjugate of affinity-purified goat anti-mouse IgG and the ribosome-inactivating protein, saporin. It uses your mouse primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Mab-ZAP is available individually (Cat. #IT-04) or as a kit (Cat. #KIT-04) which includes Mab-ZAPSaporin (Cat. #PR-01)Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.