Biotin-Z Internalization Kit

Screen Your Biotinylated Targeting Agent

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Biotin-Z Internalization Kit

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IN VITRO or IN VIVO applications provide definitive results

Targeting Agents to Extracellular Markers

For Example:

  • Antibodies
  • Peptides
  • Cytokines
  • Growth Factors
  • Lectins
  • Aptamers

Biotin-Z Internalization Kit

Use cell surface markers to bind and internalize molecules into specific cell types. Eliminating specific cell types can reveal the function of the cell and its impact on behavior.

Here’s how it works

Streptavidin is conjugated to a ribosome-inactivating protein called Saporin. Saporin is unable to enter a cell on its own. Mix the Biotinylated Molecule with the Streptavidin-Saporin conjugate. The agent is now armed and able to ZAP any cell it enters.

The Biotinylated Molecule binds to a cell surface marker and is internalized, taking the Saporin inside the cell with it. Once inside the cell, Saporin inactivates the ribosome, shutting down protein synthesis and causing cell death. Only the cells that recognize your Biotinylated Molecule will be affected.

Available Kit Options


Product: in vivo

Product: in vitro

Biotinylated Peptide

Streptavidin-ZAP Peptide Kit

Biotin-Z Peptide Internalization Kit

Biotinylated Antibody
*choose host species of your material

Streptavidin-ZAP Antibody Kit
goat, human, mouse, rat, rabbit, sheep

Biotin-Z Antibody Internalization Kit
goat, human, mouse, rat, rabbit, sheep

Other Biotinylated Material

Streptavidin-ZAP Antibody Kit

Biotin-Z Antibody Internalization Kit

View product page to view specifications
and order your Kit

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