Chick-ZAP uses your chicken IgY primary antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified rabbit anti-chicken IgY) to “piggyback” onto YOUR chicken primary antibody. Chick-ZAP be utilized for screening chicken IgY antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.
Chick-ZAP uses your chicken IgY primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.