Chick-ZAP [IT-62, KIT-62]

a tool to “piggyback” onto YOUR antibody via affinity-purified rabbit anti-chicken IgY; targeting cells that recognize YOUR primary chicken IgY antibody, eliminated via saporin

SKU: IT-62 Category: Antibody Type: affinity-purified | Host: Rabbit | Reactivity: chicken | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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Chick-ZAP uses your chicken IgY primary antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified rabbit anti-chicken IgY) to “piggyback” onto YOUR chicken primary antibody. Chick-ZAP be utilized for screening chicken IgY antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

Chick-ZAP is a chemical conjugate of affinity-purified rabbit anti-chicken IgY and the ribosome-inactivating protein, saporin. It uses your chicken IgY primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Chick-ZAP is available individually (Cat. #IT-62) or as a kit (Cat. #KIT-62) which includes Chick-ZAPSaporin (Cat. #PR-01)Rabbit IgG-SAP (Cat. #IT-35) and reagents for developing a cytotoxicity assay.