Alpaca-ZAP recognizes YOUR primary antibody. It is a chemical conjugate of goat anti-alpaca IgG (VHH domain) and the ribosome-inactivating protein, saporin. The antibodies used to make Alpaca-ZAP mouse are affinity-purified against the heavy chain of alpaca IgG (VHH domain). The antibody used in this product reacts with the VHH domain of heavy chain (HC) alpaca IgG, subclasses 2 and 3, and with the VHH domain of llama IgG, subclasses 2 and 3. It also reacts with whole molecule alpaca and llama IgG1.
Alpaca-ZAP is a chemical conjugate of goat anti-alpaca IgG (VHH domain) and the ribosome-inactivating protein, saporin. It uses your mouse primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.
Alpaca-ZAP is available individually (Cat. #IT-87) or as a kit (Cat. #KIT-87) which includes Alpaca-ZAP, Saporin (Cat. #PR-01), Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.
Other ZAP Conjugates:
keywords: Alpaca Antibody, Alpaca Primary, Anti-Alpaca IgG, Alpaca IgG, Llama, Llama IgG1, VHH domain, heavy chain, Screening, ADC, Antibody Drug Conjugate, in vitro, Secondary