Alpaca-ZAP [IT-87, KIT-87]

a tool to “piggyback” onto YOUR antibody via goat anti-alpaca IgG (VHH Domain); targeting cells that recognize YOUR primary antibody, eliminated via saporin

SKU: IT-87 Category: Host: Goat | Reactivity: Alpaca, Llama | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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Alpaca-ZAP recognizes YOUR primary antibody. It is a chemical conjugate of goat anti-alpaca IgG (VHH domain) and the ribosome-inactivating protein, saporin. The antibodies used to make Alpaca-ZAP mouse are affinity-purified against the heavy chain of alpaca IgG (VHH domain). The antibody used in this product reacts with the VHH domain of heavy chain (HC) alpaca IgG, subclasses 2 and 3, and with the VHH domain of llama IgG, subclasses 2 and 3.  It also reacts with whole molecule alpaca and llama IgG1.

Alpaca-ZAP is a chemical conjugate of goat anti-alpaca IgG (VHH domain) and the ribosome-inactivating protein, saporin. It uses your mouse primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Alpaca-ZAP is available individually (Cat. #IT-87) or as a kit (Cat. #KIT-87) which includes Alpaca-ZAPSaporin (Cat. #PR-01)Goat IgG-SAP (Cat. #IT-19) and reagents for developing a cytotoxicity assay.