Abstracts from Society for Neuroscience (SFN) November 12-16, 2011 • Washington, DC

37.06 Highly selective lesion of the cholinergic pedunculopontine neurons using a minimally-invasive angular stereotaxic surgery with the Diphteria-Urotensin-II neurotoxin in rat

M Cyr, D A Maclaren, M-A Bédard, S D Clark, N Mechawar, J Rochford, P Winn

featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov 12, 2011, 2:00 PM – 3:00 PM )

37.13 [18F] fluoroethoxybenzovesamicol (FEOBV): A reliable PET radiocompound for the in-vivo assessment of cholinergic terminals.

M Parent, P Rosa-Neto, A Aliaga, J-P Soucy, M-A Bedard,;

featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov 12, 2011, 1:00 PM – 2:00 PM )

47.02 Rapid beta-amyloid deposition and behavioural impairment after cholinergic denervation in APPswe/PS1dE9

M Pacheco-Herrero, D Thyssen, J Ramos-Rodriguez, E Berrocoso, B Bacskai, M Garcia-Alloza

featuring IT-16 mu p75-SAP (Poster; Saturday, Nov 12, 2011, 2:00 PM – 3:00 PM)

86.06 Diminished norepinephrine release in the BSTv decreases anxiety but does not promote maternal behavior in nulliparous female rats.

M A Holschbach, J S Lonstein,

featuring IT-03 Anti-DBH-SAP (Poster; Saturday, Nov 12, 2011, 2:00 PM – 3:00 PM)

88.05 Basal metabolic substrate utilization is altered by lesion of hindbrain catecholamine neurons that innervate the medial hypothalamus and substrate selection during glucoprivation is impaired.

S Ritter, A-J Li, Q Wang, T T Dinh;

featuring IT-03 Anti-DBH-SAP, PR-01 Saporin (Poster; Saturday, Nov 12, 2011, 1:00 PM – 2:00 PM)

179.16 Transmission of neuropathic pain by spinal neurons expressing the NPY Y1 receptor

R R Donahue, G F Corder, K C Mcnamara, R G Wiley, B K Taylor

featuring IT-28 NPY-SAP (Poster; Sunday, Nov 13, 2011, 11:00 AM -12:00 PM)

179.17 Activation of postsynaptic NPY Y1 and presynaptic Y2 receptors reduce spinal nociceptive transmission

G F Corder, R Donahue, M K Winter, W Chen, K E Mccarson, J Marvizon, B Taylor,

featuring IT-28 NPY-SAP (Poster; Sunday, Nov 13, 2011, 8:00 AM – 9:00 AM)

199.22 The role of medial septal/diagonal band GABAergic neurons in proactive interference: Effects of selective immunotoxic lesions in latent inhibition

S P Sinha, J J Roland, R J Servatius, K C H Pang,

featuring IT-32 GAT1-SAP (Poster; Sunday, Nov 13, 2011, 9:00 AM -10:00 AM )

232.12 Targeted ablation of intrinsically photosensitive melanopsin expressing retinal ganglion cells early in development alters retinal morphology within the inner plexiform layer of mice

D A Van Der List, B Chapman,

featuring IT-44 Melanopsin-SAP (Poster; Sunday, Nov 13, 2011, 4:00 PM – 5:00 PM)

244.02 Deficits in attentional control of balance, mobility, and complex movements in a rat model of early state, multisystem Parkinson disease

C A Spuz, G Paolone, S Briscoe, M Bradshaw, R L Albin, M F Sarter

featuring IT-01 192-IgG-SAP (Poster; Sunday, Nov 13, 2011, 2:00 PM – 3:00 PM)

249.09 Evidence that focal interneuron lesions in the hippocampus may lead to a model of epileptogenesis in the mouse.

C A Rossi, M J Lehmkuhle, F E Dudek

featuring IT-11 SSP-SAP (Poster; Sunday, Nov 13, 2011, 1:00 PM – 2:00 PM)

294.07 Cholinergic modulation of cross-modal attentional orienting

V Ljubojevic, E De Rosa, P Luu

featuring IT-01 192-IgG-SAP (Poster; Sunday, Nov 13, 2011, 3:00 PM – 4:00 PM)

296.03 The effects of noradrenergic lesions to the orbitofrontal cortex on reversal learning

A T Bates, A N Duys, C E Miller, R Miller, J Mcgaughy

featuring IT-03 Anti-DBH-SAP (Poster; Sunday, Nov 13, 2011, 3:00 PM – 4:00 PM)

331.04 Growth factor infusion increases BrdU-positive cells in the denervated medial septum following 192-IgG-saporin lesion

S S Winter, J R Köppen, J M Stout, H A Cameron, D G Wallace, J L Cheatwood

featuring IT-01 192-IgG-SAP (Poster; Monday, Nov 14, 2011, 11:00 AM -12:00 PM)

345.09 Noradrenergic neurons of the A5 region play a role on hypoxic ventilatory response in unanesthetized rats.

C L Taxini, K Bícego, A Takakura, T Moreira, L Gargaglioni

featuring IT-03 Anti-DBH-SAP (Poster; Monday, Nov 14, 2011, 8:00 AM – 9:00 AM)

396.11 Lesions targeting leptin-sensitive neurons in the mediobasal hypothalamus dissociate activity and temperature circadian rhythms.

M F Wiater, H Jansen, M Oostrom, A-J Li, T Dinh, S Ritter

featuring IT-47 Leptin-SAP, IT-21 Blank-SAP (Poster; Monday, Nov 14, 2011, 10:00 AM -11:00 AM)

397.15 Cholinergic neurons of the basal forebrain and nitric oxide-mediated regulation of sleep homeostasis.

A V Kalinchuk, T Porkka-Heiskanen, R W Mccarley, R Basheer

featuring IT-01 192-IgG-SAP (Poster; Monday, Nov 14, 2011, 10:00 AM -11:00 AM)

513.09 Role of the medial septal-diagonal band nucleus in working memory: Effects of cholinergic or GABAergic lesions on memory demand and interference

A L Stewart, J J Roland, R J Servatius, K Pang,

featuring IT-01 192-IgG-SAP, IT-32 GAT1-SAP (Poster; Monday, Nov 14, 2011, 1:00 PM – 2:00 PM)

513.10 Reduced hippocampal acetylcholine efflux after medial septal-diagonal band (MSDB) GABAergic lesion is associated with impaired working memory: behavioral and neurochemical effects of physostigmine.

J J Roland, A L Stewart, L M Savage, R J Servatius, K C H Pang,

featuring IT-32 GAT1-SAP (Poster; Monday, Nov 14, 2011, 2:00 PM – 3:00 PM)

550.01 P300-like event related potentials in IgG192-saporin induced rat model of Alzheimer´s disease

B Clausen, W Klipec, J Bastlund, M Collins

featuring IT-01 192-IgG-SAP (Poster; Tuesday, Nov 15, 2011, 8:00 AM – 9:00 AM)

600.13 Lesions targeting leptin-sensitive neurons in the ventromedial and suprachiasmatic nuclei differentiate sites for circadian control of feeding

T T Dinh, B R Smith, M F Wiater, H Jansen, A-J Li, S Ritter

featuring IT-47 Leptin-SAP (Poster; Tuesday, Nov 15, 2011, 8:00 AM – 9:00 AM )

600.17 Fourth ventricular glucosamine-induced feeding is catecholamine-dependent

A-J Li, Q Wang, S Ritter

featuring IT-03 Anti-DBH-SAP (Poster; Tuesday, Nov 15, 2011, 8:00 AM – 9:00 AM)

608.16 Cholinergic reinforcement and temporal learning in rodent visual cortex

E B Roach, M G Hussain Shuler

featuring IT-01 192-IgG-SAP (Poster; Tuesday, Nov 15, 2011, 11:00 AM -12:00 PM)

610.12 Cognitive performance-associated increases in cholinergic neurotransmission also serve as a circadian signal to sustain performance-induced diurnal activity patterns.

G Paolone, D Lamy, M Sarter, T Lee

featuring IT-01 192-IgG-SAP (Poster; Tuesday, Nov 15, 2011, 11:00 AM -12:00 PM)

664.14 Cardiovascular dysfunction and cardiac injury result from selective glial damage in the nucleus tractus solitarii

W T Talman, D Nitschke Dragon, S Jones, S A Moore, L-H Lin

featuring IT-03 Anti-DBH-SAP, IT-11 SSP-SAP, IT-18 Mouse IgG-SAP, IT-21 Blank-SAP, PR-01 Saporin (Poster; Tuesday, Nov 15, 2011, 2:00 PM – 3:00 PM)

702.10 The role of descending facilitation in the initiation and maintenance of mechanical hypersensitivity following inflammation

F Carr, S M Géranton, S P Hunt

featuring IT-12 Dermorphin-SAP (Poster; Tuesday, Nov 15, 2011, 2:00 PM – 3:00 PM)

712.07 Arcuate NK3 receptor-expressing KNDy neurons are essential for estrogen modulation of LH secretion and body weight in the female rat [Read Abstracts]

M A Smith, H Williams, S J Krajewski, N T Mcmullen, N E Rance

featuring Experimental Material NKB-SAP, IT-21 Blank-SAP (Poster; Tuesday, Nov 15, 2011, 3:00 PM – 4:00 PM)

712.09 Ablation of NK3 receptor-expressing KNDy neurons in the rat arcuate nucleus using [MePhe⁷]Neurokinin B-Saporin [Read Abstracts]

S J Krajewski, M A Smith, H Williams, P Ciofi, J Y Lai, N T Mcmullen, N E Rance

featuring Experimental Material NKB-SAP, IT-21 Blank-SAP (Poster; Tuesday, Nov 15, 2011, 1:00 PM – 2:00 PM)

790.01 Alterations in gene expression following cortical cholinergic denervation in rats

S T Savage, L Olson, A Mattsson

featuring IT-01 192-IgG-SAP (Poster; Wednesday, Nov 16, 2011, 8:00 AM – 9:00 AM)

804.14 Selective activation of dorsal horn inhibitory interneurons produces anti-nociception

R G Wiley, D A Lappi

featuring IT-56 Neurotensin-SAP, IT-60 Neurotensin-CTA(Poster; Wednesday, Nov 16, 2011, 9:00 AM -10:00 AM)

804.21 Consequences of the ablation of non-peptidergic nociceptive fibers on neurokinin-1 receptor expression by spinal lamina I neurons

A W Saeed, A Ribeiro-Da-Silva

featuring IT-10 IB4-SAP (Poster; Wednesday, Nov 16, 2011, 8:00 AM – 9:00 AM)

822.19 Leptin-receptor-expressing neurons in the non-preganglionic Edinger-Westphal nucleus regulate white and brown adipose tissue

T Kozicz, L Xu, B Geenen, B Gaszner, K Kovacs, E Roubos

featuring IT-47 Leptin-SAP, IT-21 Blank-SAP (Poster; Wednesday, Nov 16, 2011, 10:00 AM -11:00 AM)

878.08 Decrease of GABAergic markers and Arc protein expression in the frontal cortex by injection of intraventricular 192 IgG-saporin

D Jeong, W Chang, D Lee, J Chang

featuring IT-01 192-IgG-SAP (Poster; Wednesday, Nov 16, 2011, 4:00 PM – 5:00 PM )

878.10 The effects of basal forebrain cholinergic neuron on novel object recognition

J Lee, D Jeong, J Chang

featuring IT-01 192-IgG-SAP (Poster; Wednesday, Nov 16, 2011, 2:00 PM – 3:00 PM)

883.20 Norepinephrine denervation by dopamine beta-hydroxylase saporin impacts L-DOPA efficacy and side effects in a hemi-parkinsonian rat model

N S Bhide, S Dickinson, E Feinberg, M Mohamed, K Dupre, K Eskow-Jaunarajs, D Lindenbach, C Ostock, C Bishop

featuring IT-03 Anti-DBH-SAP (Poster; Wednesday, Nov 16, 2011, 4:00 PM – 5:00 PM)

901.09 The nucleus incertus contributes to the anxiety-like behaviour in rats

C Lee, R Rajkumar, S Suri, W M Chin, G S Dawe

featuring IT-13 CRF-SAP (Poster; Wednesday, Nov 16, 2011, 1:00 PM – 2:00 PM)