Author name: Kristen Hartman

CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice

Herrerias A, Oliverio A, Dvorácskó S, Thyagarajan A, Chedester L, Liu J, Cinar R, Iyer MR, Kunos G, Godlewski G (2025) CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice. Mol Psychiatry doi: 10.1038/s41380-025-03266-9 PMID: 40975751 Related Products: Anti-CB1-SAP (Cat. #IT-104), Blank-SAP (Cat. #IT-21)

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Melanopsin Antibody Recent Publications

We’re highlighting one of our antibodies, a rabbit polyclonal against Melanopsin. This antibody is offered as both serum (AB-N38) and affinity purified (AB-N39). Intrinsically photosensitive retinal ganglion cells (ipRGCs) are cells that express melanopsin. These ipRGCs, with their long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Our

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How many antibody molecules can ZAP bind to? What’s the recommended concentration?

Question I am using your Fab-ZAP Human (IT-51) and I want to know how many antibody molecules can a secondary antibody conjugate theoretically bind to? Answer A whole IgG (bivalent) secondary antibody in theory is capable of binding two antigen molecules.  Since our Fab-ZAP conjugates actually use a monovalent secondary antibody, in theory they would

How many antibody molecules can ZAP bind to? What’s the recommended concentration? Read More »

Meningeal macrophages mask incision pain sensitization in male rats

Kolahdouzan M, Ghazisaeidi S, Tu Y, Muley M, Gambeta E, Salter M (2025) Meningeal macrophages mask incision pain sensitization in male rats. Mol Pain doi: 10.1177/17448069251383593 Objective: To investigate whether CD206+macrophages in the meninges play a role in regulating nociception and pain hypersensitivity. Summary: The results indicate that while CD206+ meningeal macrophages do not regulate

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Development of a targeted choroidal injury model for the study of retinal degenerations and therapeutic cell replacement

Pandala N, De Melo Haefeli L, Lang M, Stone EM, Mullins RF, Tucker BA, Han IC (2025) Development of a targeted choroidal injury model for the study of retinal degenerations and therapeutic cell replacement. bioRxiv 2025.07.29.667466. doi: 10.1101/2025.07.29.667466 Summary: The choroid is a vascular structure that provides nutrients to the photoreceptors by diffusion as well

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