- Saporin conjugates require a targeting agent that is recognized on the cell surface and specific to the cell type to be studied.
- The most common targeting agent is an antibody.
- How do you know if your antibody will make a good targeting agent?
- ATS has a product line of secondary antibody conjugates to help screen and identify your targeting agent.
- These ZAP products are available for multiple species.
- Mix your antibody with the proper ZAP product and you’ve just made your own immunotoxin.
- Perform a cytotoxicity assay to ensure your antibody is specific to the cell type to be eliminated.
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