Author name: Kristen Hartman

Retinal glia regulate development of the circadian photoentrainment circuit

Brown TW, Vilallongue N, Hales SC, Srikanta S, Rochon PL, Rangel Olguin AG, Waxman SB, Tufford A, Van Prooijen J, Krishnaswamy A, Cermakian N, Cayouette M (2025) Retinal glia regulate development of the circadian photoentrainment circuit. Cell Rep 44(11):116464. doi: 10.1016/j.celrep.2025.116464 PMID: 41150857 Objective: To examine the role of Müller glia in the development of […]

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Progress, opportunity, and perspective on long term preservation of extracellular vesicles

Du R, Zhang Y, Wu S, Zixing W, Jing W (2025) Progress, opportunity, and perspective on long term preservation of extracellular vesicles. SSRN ssrn.5553381. doi: 10.2139/ssrn.5553381 Objective: To provide an overview of the biology, function, and biomedical application of Extracellular vesicles (EVs) and introduce the method to evaluate the storage stability of EVs. Summary: While

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Cerebellar contributions to spatial learning and memory: Effects of discrete immunotoxic lesions

Leanza MH, Storelli E, D’Arco D, de Leo G, Kleiner G, Arancio L, Capodieci G, Gulino R, Bava A, Leanza G (2025) Cerebellar contributions to spatial learning and memory: Effects of discrete immunotoxic lesions. Int J Mol Sci 26(19):9553. doi: 10.3390/ijms26199553 PMID: 41096819 Objective: To analyze the behavioral and anatomical effects of discrete injections, in

Cerebellar contributions to spatial learning and memory: Effects of discrete immunotoxic lesions Read More »

CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice

Herrerias A, Oliverio A, Dvorácskó S, Thyagarajan A, Chedester L, Liu J, Cinar R, Iyer MR, Kunos G, Godlewski G (2025) CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice. Mol Psychiatry doi: 10.1038/s41380-025-03266-9 PMID: 40975751 Related Products: Anti-CB1-SAP (Cat. #IT-104), Blank-SAP (Cat. #IT-21)

CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice Read More »

Light-enhanced cytotoxicity and intracellular trafficking of the PD-L1-targeting photoimmunoconjugate EITC-atezolizumab

Alampi MM, Kozlíková M, Mariangeli M, Civita S, Delcanale P, Mussini A, Diaspro A, Bianchini P, Weyergang A, Skarpen E, Berg K, Viappiani C, Abbruzzetti S, Selbo PK (2025) Light-enhanced cytotoxicity and intracellular trafficking of the PD-L1-targeting photoimmunoconjugate EITC-atezolizumab. Biomed Pharmacother 191:118550. doi: 10.1016/j.biopha.2025.118550 PMID: 40946581 Objective: To optimize the cytotoxic efficacy of a photoimmunoconjugate

Light-enhanced cytotoxicity and intracellular trafficking of the PD-L1-targeting photoimmunoconjugate EITC-atezolizumab Read More »

Melanopsin Antibody Recent Publications

We’re highlighting one of our antibodies, a rabbit polyclonal against Melanopsin. This antibody is offered as both serum (AB-N38) and affinity purified (AB-N39). Intrinsically photosensitive retinal ganglion cells (ipRGCs) are cells that express melanopsin. These ipRGCs, with their long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Our

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Focal irradiation regulates distal neural stem and progenitor cell behaviour

Handfield J (2025) Focal irradiation regulates distal neural stem and progenitor cell behaviour. Univ Toronto Thesis. Objective: To investigate how focal irradiation (IR) impacts non-irradiated neural stem cell (NSC) niches along the neuraxis and whether microglia mediate these long-distance effects. Summary: Focal cranial IR decreased spinal cord-derived NSCs, while spinal IR reduced neuroblasts and NSCs

Focal irradiation regulates distal neural stem and progenitor cell behaviour Read More »

Investigating anxiety-like behaviors and basolateral amygdala dysfunction in a novel rat model of Parkinson’s disease

Lipari NR (2025) Investigating anxiety-like behaviors and basolateral amygdala dysfunction in a novel rat model of Parkinson’s disease. SUNY Binghamton Thesis. Objective: To create a unique model of PD with improved face validity, and non-motor symptoms. Summary: This work helped further characterize motor and non-motor symptoms while providing potential underlying physiological markers for early disease

Investigating anxiety-like behaviors and basolateral amygdala dysfunction in a novel rat model of Parkinson’s disease Read More »

Hole in one: CD137-ADC eliminates GVHD

Nierkens S, Lindemans CA (2025) Hole in one: CD137-ADC eliminates GVHD. Blood 146(9):1038-1040. doi: 10.1182/blood.2025029867 PMID: 40875553 Objective: To show that a single dose of CD137-ADC can prevent acute graft-versus-host disease (GVHD) while pre-serving immune reconstitution in a nonhuman primate (NHP) model of stem cell transplantation. Summary: Results showed that animals treated with CD137-ADC exhibited

Hole in one: CD137-ADC eliminates GVHD Read More »

Assessing the hematological cancer stem cell landscape to improve immunotherapy clinical decisions

Diamantoudis SC, Miliotou AN, Galatou E, Telliou S, Sideris K, Grigoriadis N, Vizirianakis IS (2025) Assessing the hematological cancer stem cell landscape to improve immunotherapy clinical decisions. Biocell doi: 10.32604/biocell.2025.067216 Objective: To combine existing information and clinical evidence to assess and bring to the spotlight targets related to Hematological cancer stem cells (HCSCs) that can

Assessing the hematological cancer stem cell landscape to improve immunotherapy clinical decisions Read More »

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