CD206-positive meningeal macrophages prevent the spread of pain hypersensitivity after a minor injury
episode18, episode42
Visualization of endosomal escape of intracellularly delivered protein with unexpected photochemical internalization of trypan blue
Yao Z, Shi Z, Hu P, Wang C, Wang H (2026) Visualization of endosomal escape of intracellularly delivered protein with unexpected photochemical internalization of trypan blue. Adv Sci (Weinh) e16456. doi: 10.1002/advs.202516456 PMID: 41961480 Objective: To demonstrate trypan blue as a simple yet powerful tool for advancing intracellular protein delivery and tracking. Summary: Upon 590
In utero HSC transplantation for sickle cell disease: A potential therapeutic approach that overcomes complications of current therapies
Babatunde OO, Bibby MG, Atala A, Almeida-Porada G, Porada CD (2026) In utero HSC transplantation for sickle cell disease: A potential therapeutic approach that overcomes complications of current therapies. Prenat Diagn doi: 10.1002/pd.70142 PMID: 41936060 Objective: To examine current evidence and recent advances for treatment of sickle cell disease (SCD). Summary: Biotinylated anti‐c‐kit/CD117 mAb coupled
Photodynamic therapy-based strategies targeted at cancer stem cells: A scoping review
Serambeque B, Dias I, Mestre C, Marto CM, Botelho MF, Carvalho MJ, Laranjo M (2026) Photodynamic therapy-based strategies targeted at cancer stem cells: A scoping review. Cancers (Basel) 18(7):1162. doi: 10.3390/cancers18071162 PMID: 41976384 Objective: To examine strategies for targeting cancer stem cells using photodynamic therapy. Summary: Photochemical internalization (PCI) is a widely adopted approach for
Photodynamic therapy-based strategies targeted at cancer stem cells: A scoping review Read More »
Intestinal interoceptive dysfunction drives age-associated cognitive decline
Cox TO, Devason AS, de Araujo A, Mason S, Subramanian M, Salvador AFM, Descamps HC, Kim J, Zhu Y, Litichevskiy L, Jung S, Song WS, Cortés-Martín A, Henderson NT, Huang KP, Nguyen T, Sae-Lee W, Umana IC, Sacta M, Rahman RJ, Wisser S, Nelson JAD, Golynker I, McSween AM, Hohmann EF, Patel S, Bub AL,
Intestinal interoceptive dysfunction drives age-associated cognitive decline Read More »
Sex differences in the effects of etonogestrel on respiratory recovery in an in vivo rat model of central chemoreflex impairment
Cardani S, Janes TA, Asif R, Pagliardini S (2026) Sex differences in the effects of etonogestrel on respiratory recovery in an in vivo rat model of central chemoreflex impairment. Acta Physiol (Oxf) 242(4):e70194. doi: 10.1111/apha.70194 PMID: 41823358 Objective: Chronic etonogestrel (ETO) treatment improved the CO2 chemoreflex in female rats in which
Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines
Kozlíková M, Aukrust IKF, Rohlíčková M, Macháček M, Berg K, Weyergang A, Selbo PK (2026) Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. Front Immunol 17:1750003. doi: 10.3389/fimmu.2026.1750003 PMID: 41909645 Objective: To investigate photochemical internalization (PCI), a light–controlled endosomal escape technology, as a strategy to enhance intracellular delivery and efficacy