Cardani S, Janes TA, Asif R, Pagliardini S (2026) Sex differences in the effects of etonogestrel on respiratory recovery in an in vivo rat model of central chemoreflex impairment. Acta Physiol (Oxf) 242(4):e70194. doi: 10.1111/apha.70194 PMID: 41823358 Objective: Chronic etonogestrel (ETO) treatment improved the CO2 chemoreflex in female rats in which
Cox TO, Devason AS, de Araujo A, Mason S, Subramanian M, Salvador AFM, Descamps HC, Kim J, Zhu Y, Litichevskiy L, Jung S, Song WS, Cortés-Martín A, Henderson NT, Huang KP, Nguyen T, Sae-Lee W, Umana IC, Sacta M, Rahman RJ, Wisser S, Nelson JAD, Golynker I, McSween AM, Hohmann EF, Patel S, Bub AL,
Intestinal interoceptive dysfunction drives age-associated cognitive decline Read More »
Kozlíková M, Aukrust IKF, Rohlíčková M, Macháček M, Berg K, Weyergang A, Selbo PK (2026) Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines. Front Immunol 17:1750003. doi: 10.3389/fimmu.2026.1750003 PMID: 41909645 Objective: To investigate photochemical internalization (PCI), a light–controlled endosomal escape technology, as a strategy to enhance intracellular delivery and efficacy
Lim-Paik C, Zeng Q, Beyea R, Boohaker R, Wang P (2026) Improving cytotoxicity of saporin with saponin SO1406 isolated from the roots of saponaria officinalis. Biomedicines 14(3):626. doi: 10.3390/biomedicines14030626 Objective: To identify structurally defined novel natural saponins and evaluate their ability to enhance anticancer cytotoxicity. Summary: Saponins have recently emerged as promising natural products that
Chen J, Xu T, Zhang C, Li L, He Y, Sun Z, He J, Yao Z, Cai P, Huang Y, Ye F, Guo W, Jia M, Qu J, Chen JF, Zhang Y (2026) 40 Hz light flickering alleviates chronic pain via adenosine signaling in the retina-amygdala pathway. Cell Res doi: 10.1038/s41422-026-01227-7 PMID: 41781500 Objective: To
Xiang H, Mortenson GP, Lang SB, Jakkaraju S, Chirala A, Zhu Y, Jia M, Wen J, Chen Y, Baghela A, Chen YC, Sze MA, Hegde LG, Zhang-Hoover J, Willingham A, Handa M, Chi A, Baltus GA, Kamath RV, Levesque M, Vollmann EH (2026) uPAR-targeting cytotoxic antibody–drug conjugates selectively deplete proinflammatory myeloid cells for autoimmune indications.
Hamakubo S, Komatsu N, Kosai A, Kuroda M, Sawada M, Shimizu R, Ohashi R, Suenaga H, Hamakubo T, Abe T (2026) Enhanced antitumor efficacy of a combination of immunotoxin and photosensitizer under illumination in xenograft mice. Biomedicines 14:573. doi: 10.3390/biomedicines14030573 Objective: To investigate the in vivo therapeutic efficacy of intelligent Targeted Antibody Phototherapy (iTAP), utilizing