Exploring the potential of nanogels: From drug carriers to radiopharmaceutical agents
Kubeil M, Suzuki Y, Casulli MA, Kamal R, Hashimoto T, Bachmann M, Hayashita T, Stephan H (2023) Exploring the potential of nanogels: From drug carriers to radiopharmaceutical agents. Adv Healthc Mater e2301404. doi: 10.1002/adhm.202301404 PMID: 37717209 Summary: This review provides a brief overview of current developments of nanogels in the fields of drug delivery, therapeutic
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Validated Antibodies: NGFR & Melanopsin
Validated Antibodies targeting NGFR and Melanopsin NGFR Antibodies NGFR (mu p75) Rabbit Polyclonal [AB-N01] AB-N01 also known as mu p75, and the affinity-purified version, AB-N01AP recognize the p75 receptor in mouse. Applications include immunohistochemistry, immunoprecipitation, immunoblotting, flow cytometry, and blocking the function of nerve growth factor receptor. NGFR (ME20.4, p75) Mouse Monoclonal [AB-N07] AB-N07 also known
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Nucleolin‑based targeting strategies in cancer treatment: Focus on cancer immunotherapy (Review)
Thongchot S, Aksonnam K, Thuwajit P, Yenchitsomanus PT, Thuwajit C (2023) Nucleolin‑based targeting strategies in cancer treatment: Focus on cancer immunotherapy (Review). Int J Mol Med 52(3):81. doi: 10.3892/ijmm.2023.5284 PMID: 37477132 Objective: The authors review the mechanisms through which the multiple functions of NCL can participate in the progression of cancer. In addition, the studies
pHast Conjugate Videos
pHast Conjugate Videos An introduction to our pHast product line: pH-sensitive fluorescent secondary conjugates designed to fluoresce when exposed to the environment inside of a cell. Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish Also available in Chinese | French | German | Italian |
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Screening targeting agents and their cell surface biomarkers for high specificity and rapid internalization via cell death and fluorescence.
Screening targeting agents and their cell surface biomarkers for high specificity and rapid internalization via cell death and fluorescence. Ancheta L, Bouajram R, Lappi DA (2018) Society for Neuroscience, San Diego, CA. Abstract Some of the most recent successes in the treatment of cancers or research into passive immunotherapies for neurodegenerative diseases, employ the use
Emerging non-viral vectors for gene delivery
Wang C, Pan C, Yong H, Wang F, Bo T, Zhao Y, Ma B, He W, Li M (2023) Emerging non-viral vectors for gene delivery. J Nanobiotechnology 21(1):272. doi: 10.1186/s12951-023-02044-5 PMID: 37592351 Summary: This review describes the fastest-growing and efficient non-viral gene delivery vectors that include liposomes and lipid nanoparticles (LNPs), highly branched poly(β-amino ester)
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Novel approaches towards cancer-directed immune checkpoint inhibition
Ploeg E (2023) Novel approaches towards cancer-directed immune checkpoint inhibition. Univ Groningen Thesis. doi: 10.33612/diss.737906343 Objective: To evaluate a novel bispecific antibody, bsAb CD73xEGFR, that inhibits the immunosuppressive enzyme CD73 on cancer cells in an EGFR-directed manner. Summary: The researchers constructed a bispecific antibody, bsAb CD73xEGFR, that binds to both CD73 and EGFR on cancer
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Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases
Jin X, Yang GY (2023) Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases. Prog Lipid Res 101241. doi: 10.1016/j.plipres.2023.101241 PMID: 37524133 Objective: The authors review the tumor-related biological functions of GSLs and recent progress in using GSLs and related enzymes to diagnose and treat tumor diseases. Summary: Glycosphingolipids (GSLs)