Time Course for Saporin Conjugates
episode27, episode49
Time Course for Saporin Conjugates Read More »
Three categories of ZAP conjugates
episode25, episode47
Three categories of ZAP conjugates Read More »
Summarizing the role of selected adipokines in parkinson’s disease: What is known about leptin, adiponectin, resistin, visfatin, and progranulin in neurodegeneration?
Milanowski J, Pawłowska M, Woźniak A, Szewczyk-Golec K (2025) Summarizing the role of selected adipokines in parkinson’s disease: What is known about leptin, adiponectin, resistin, visfatin, and progranulin in neurodegeneration?. Molecules 30(22):4431. doi: 10.3390/molecules30224431 PMID: 41302488 Objective: To summarize current evidence and identify potential targets for Parkinson’s disease (PD) treatment or as biomarkers of disease
Electroacupuncture alleviates cognitive impairments in APP/PS1 mice via gastric vagal afferent-mediated activation of the nucleus tractus solitarius‒locus coeruleus noradrenergic circuit
Yu C, Li M, Shen F, Gao S, Wang J, He C, Wang L, Wu Y, Du Y (2025) Electroacupuncture alleviates cognitive impairments in APP/PS1 mice via gastric vagal afferent-mediated activation of the nucleus tractus solitarius‒locus coeruleus noradrenergic circuit. Chin Med 20(1):188. doi: 10.1186/s13020-025-01230-x PMID: 41233833 Objective: To demonstrate efficacy in ameliorating Alzheimer’s disease (AD)-related
Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution?
Spedding M (2025) Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution?. Cells 14(21):1734. doi: 10.3390/cells14211734 PMID: 41227379 Objective: To evaluate if recent human genetic variants play major roles in Amyotrophic Lateral Sclerosis (ALS), changing metabolism. Summary: The authors reviewed Cholera Toxin B (CTB) binding as a tool to study GM1 and fucosylated
Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution? Read More »
Immune tolerance induction using the thyrotropin receptor epitope 78-94 (p37) prevents Graves’ disease in HLA-DR3 transgenic mice
Inaba H, Nonaka I, Hashimoto D, Hirono M, Morita S, Kimura H, Iwakura H, Akamizu T, Nakata M (2025) Immune tolerance induction using the thyrotropin receptor epitope 78-94 (p37) prevents Graves’ disease in HLA-DR3 transgenic mice. Front Immunol 16:1633350. doi: 10.3389/fimmu.2025.1633350 PMID: 41256857 Objective: To investigate whether pre-immunization with the immunodominant TSH-R–derived peptide spanning residues
Real-time in vivo monitoring of cholinergic neurotransmission in the mouse brain using a microelectrochemical choline biosensor
Doyle S, Doran MM, Cunningham C, Lowry JP (2025) Real-time in vivo monitoring of cholinergic neurotransmission in the mouse brain using a microelectrochemical choline biosensor. Eur J Neurosci 62)9):e70291. doi: 10.1111/ejn.70291 PMID: 41185145 Objective: To refine an established choline oxidase (ChOx) microelectrochemical biosensor to validate its use for long-term recording in the freely moving mouse.