Tateda Y, Suzuki T, Sato T, Izuhara K, Ise K, Shimada H, Murakami K, Murakami K, Nakamura Y, Ohta N (2025) Immunohistochemical localization of D-β-aspartic acid and periostin in benign parotid gland tumors. Histol Histopathol 25013. doi: 10.14670/HH-25-013 PMID: 41178409 Objective: To investigate the expression and role of D-β-aspartic acid and periostin in the formation […]
Brown TW, Vilallongue N, Hales SC, Srikanta S, Rochon PL, Rangel Olguin AG, Waxman SB, Tufford A, Van Prooijen J, Krishnaswamy A, Cermakian N, Cayouette M (2025) Retinal glia regulate development of the circadian photoentrainment circuit. Cell Rep 44(11):116464. doi: 10.1016/j.celrep.2025.116464 PMID: 41150857 Objective: To examine the role of Müller glia in the development of
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Yelamali AR, Chendamarai E, Ritchey JK, Rettig MP, DiPersio JF, Persaud SP (2025) Streptavidin-drug conjugates streamline optimization of antibody-based hematopoietic stem cell transplant conditioning. Blood ICT 1(3):100012. doi: 10.1016/j.bict.2025.100012 PMID: 41574174 Objective: To develop and validate a modular streptavidin based antibody drug conjugate platform for optimizing antibody mediated hematopoietic stem cell transplant conditioning. Summary: The
Park JS, Kenum C, He L, Khan AG, Pohl MA, White TE, Kodangattil SR, Rudin CM, Balderes PJ, Lorenz IC, Massagué J, anesh K (2025) Development of antibody-drug conjugates targeting L1CAM to treat metastatic cancer. bioRxiv 2025.10.01.679843. doi: 10.1101/2025.10.01.679843 PMID: 41256399 Objective: To develop L1CAM-targeted antibody-drug conjugates (ADCs) using high-affinity monoclonal antibodies and assess their
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Du R, Zhang Y, Wu S, Zixing W, Jing W (2025) Progress, opportunity, and perspective on long term preservation of extracellular vesicles. SSRN ssrn.5553381. doi: 10.2139/ssrn.5553381 Objective: To provide an overview of the biology, function, and biomedical application of Extracellular vesicles (EVs) and introduce the method to evaluate the storage stability of EVs. Summary: While
Gan JH, Wang MJ, Li CY, Huang Y, Liu ZH, Bai WL, Xu WJ, Sun MH, Kang MT, Morgan I, Wang N, Li SM (2025) The interplay between form deprivation and dopamine signaling in regulating the expression of circadian rhythm-related genes in the retina of mice. Graefes Arch Clin Exp Ophthalmol doi: 10.1007/s00417-025-06950-2 PMID: 41026222
Leanza MH, Storelli E, D’Arco D, de Leo G, Kleiner G, Arancio L, Capodieci G, Gulino R, Bava A, Leanza G (2025) Cerebellar contributions to spatial learning and memory: Effects of discrete immunotoxic lesions. Int J Mol Sci 26(19):9553. doi: 10.3390/ijms26199553 PMID: 41096819 Objective: To analyze the behavioral and anatomical effects of discrete injections, in
Herrerias A, Oliverio A, Dvorácskó S, Thyagarajan A, Chedester L, Liu J, Cinar R, Iyer MR, Kunos G, Godlewski G (2026) CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice. Mol Psychiatry 31(1):48-61. doi: 10.1038/s41380-025-03266-9 PMID: 40975751 Objective: To investigate how peripheral CB1 receptors on vagal afferent neurons regulate
Kobayashi K, Miyazaki Y, Sakamoto N, Yamamoto M, Nagat N, Murata T (2025) Long-term scratching analysis of mice using machine learning. PNAS Nexus 4(9):pgaf292. doi: 10.1093/pnasnexus/pgaf292 PMID: 41030291 Objective: To objectively quantify mouse scratching behavior across light and dark cycles using automated, long-term machine learning analysis. Summary: Naïve BALB/c mice exhibited more frequent and persistent
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Alampi MM, Kozlíková M, Mariangeli M, Civita S, Delcanale P, Mussini A, Diaspro A, Bianchini P, Weyergang A, Skarpen E, Berg K, Viappiani C, Abbruzzetti S, Selbo PK (2025) Light-enhanced cytotoxicity and intracellular trafficking of the PD-L1-targeting photoimmunoconjugate EITC-atezolizumab. Biomed Pharmacother 191:118550. doi: 10.1016/j.biopha.2025.118550 PMID: 40946581 Objective: To optimize the cytotoxic efficacy of a photoimmunoconjugate