Three categories of ZAP conjugates
episode25, episode47
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Summarizing the role of selected adipokines in parkinson’s disease: What is known about leptin, adiponectin, resistin, visfatin, and progranulin in neurodegeneration?
Milanowski J, Pawłowska M, Woźniak A, Szewczyk-Golec K (2025) Summarizing the role of selected adipokines in parkinson’s disease: What is known about leptin, adiponectin, resistin, visfatin, and progranulin in neurodegeneration?. Molecules 30(22):4431. doi: 10.3390/molecules30224431 PMID: 41302488 Objective: To summarize current evidence and identify potential targets for Parkinson’s disease (PD) treatment or as biomarkers of disease
Electroacupuncture alleviates cognitive impairments in APP/PS1 mice via gastric vagal afferent-mediated activation of the nucleus tractus solitarius‒locus coeruleus noradrenergic circuit
Yu C, Li M, Shen F, Gao S, Wang J, He C, Wang L, Wu Y, Du Y (2025) Electroacupuncture alleviates cognitive impairments in APP/PS1 mice via gastric vagal afferent-mediated activation of the nucleus tractus solitarius‒locus coeruleus noradrenergic circuit. Chin Med 20(1):188. doi: 10.1186/s13020-025-01230-x PMID: 41233833 Objective: To demonstrate efficacy in ameliorating Alzheimer’s disease (AD)-related
Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution?
Spedding M (2025) Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution?. Cells 14(21):1734. doi: 10.3390/cells14211734 PMID: 41227379 Objective: To evaluate if recent human genetic variants play major roles in Amyotrophic Lateral Sclerosis (ALS), changing metabolism. Summary: The authors reviewed Cholera Toxin B (CTB) binding as a tool to study GM1 and fucosylated
Does amyotrophic lateral sclerosis (als) have metabolic causes from human evolution? Read More »
Real-time in vivo monitoring of cholinergic neurotransmission in the mouse brain using a microelectrochemical choline biosensor
Doyle S, Doran MM, Cunningham C, Lowry JP (2025) Real-time in vivo monitoring of cholinergic neurotransmission in the mouse brain using a microelectrochemical choline biosensor. Eur J Neurosci 62)9):e70291. doi: 10.1111/ejn.70291 PMID: 41185145 Objective: To refine an established choline oxidase (ChOx) microelectrochemical biosensor to validate its use for long-term recording in the freely moving mouse.
Immune tolerance induction using the thyrotropin receptor epitope 78-94 (p37) prevents Graves’ disease in HLA-DR3 transgenic mice
Inaba H, Nonaka I, Hashimoto D, Hirono M, Morita S, Kimura H, Iwakura H, Akamizu T, Nakata M (2025) Immune tolerance induction using the thyrotropin receptor epitope 78-94 (p37) prevents Graves’ disease in HLA-DR3 transgenic mice. Front Immunol 16:1633350. doi: 10.3389/fimmu.2025.1633350 PMID: 41256857 Objective: To investigate whether pre-immunization with the immunodominant TSH-R–derived peptide spanning residues
Immunohistochemical localization of D-β-aspartic acid and periostin in benign parotid gland tumors
Tateda Y, Suzuki T, Sato T, Izuhara K, Ise K, Shimada H, Murakami K, Murakami K, Nakamura Y, Ohta N (2025) Immunohistochemical localization of D-β-aspartic acid and periostin in benign parotid gland tumors. Histol Histopathol 25013. doi: 10.14670/HH-25-013 PMID: 41178409 Objective: To investigate the expression and role of D-β-aspartic acid and periostin in the formation
Retinal glia regulate development of the circadian photoentrainment circuit
Brown TW, Vilallongue N, Hales SC, Srikanta S, Rochon PL, Rangel Olguin AG, Waxman SB, Tufford A, Van Prooijen J, Krishnaswamy A, Cermakian N, Cayouette M (2025) Retinal glia regulate development of the circadian photoentrainment circuit. Cell Rep 44(11):116464. doi: 10.1016/j.celrep.2025.116464 PMID: 41150857 Objective: To examine the role of Müller glia in the development of
Retinal glia regulate development of the circadian photoentrainment circuit Read More »