Abstracts from Society for Neuroscience (SFN) – San Diego, CA | November 10-15, 2001

25.9 NESTIN EXPRESSION IN NEURONS OF THE MEDIAL SEPTUM/DIAGONAL BAND IN THE ADULT RAT.

J.Yan*; D.L.Price; V.E.Koliatsos

featuring IT-01 192-IgG-SAP (Poster)

55.4 INTRATHECAL INFUSION OF SUBSTANCE P-SAPORIN ABLATES SUBSTANCE P RECEPTOR EXPRESSING NEURONS IN THE DORSAL HORN OF THE SPINAL CORD AND ATTENUATES BONE CANCER PAIN.

N.M.Luger1; M.C.Sabino1; M.J.Schwei1; S.D.Rogers1; J.D.Pomonis1; C.P.Keyser1; D.B.Mach1; J.Salak-Johnson*2; D.R.Clohisy1; P.W.Mantyh1

featuring IT-07 SP-SAP (Poster)

84.13 MEMORY ENHANCEMENT INDUCED BY POST-TRAINING NOREPINEPHRINE IN THE BASOLATERAL AMYGDALA IS BLOCKED BY 192-IGG SAPORIN LESIONS OF THE NUCLEUS BASALIS MAGNOCELLULARIS.

A.E.Power*1,2; L.J.Thal3; J.L.McGaugh1,2

featuring IT-01 192-IgG-SAP (Poster)

85.13 THE EFFECTS OF 192 IGG-SAPORIN LESIONS TO THE NUCLEUS BASALIS MAGNOCELLULARIS/SUBSTANTIA INNOMINATA (NBM/Si) ON TWO LEARNING SET FORMATION TASKS AND OPEN FIELD ACTIVITY.

A.M.Bailey*; M.L.Rudisill; E.M.Hoof; M.L.Loving

featuring IT-01 192-IgG-SAP (Poster)

101.11 CYCLOSPORINE-A IMPROVES PERFORMANCE IN PASSIVE AVOIDANCE TASK IN ADULT RATS WITH BASAL FOREBRAIN LESIONS.

C.E.Stahl1,4; T.Kusayama2; M.Keep3; E.Elmer3; S.Watanabe2; C.V.Borlongan*4

featuring IT-01 192-IgG-SAP (Poster)

101.17 DIFFERENTIAL DENDRITIC ATROPHY IN FRONTAL CORTEX AFTER CHOLINERGIC LESION IN YOUNG ADULT AND AGED RATS.

S.J.Works1; C.L.Wellman*1,2

featuring IT-01 192-IgG-SAP (Poster)

131.4 TARGETED DESTRUCTION OF A2/C2 CATECHOLAMINE NEURONS ALTERS HYPOTHALAMIC RESPONSES TO VAGAL STIMULATION.

L.Rinaman*; C.P.Wonders

featuring IT-03 Anti-DBH-SAP (Slide)

145.1 SEPTAL INNERVATION OF THE HIPPOCAMPUS REGULATES EXPRESSION a7 NICOTINIC RECEPTORS IN Ca1 AND Ca3 PYRAMIDAL NEURONS.

A.L.Camara1,2; E.F.Pereira1; M.Alkondon1; W.R.Randall1; N.G.Castro3; W.M.Cintra*3; E.X.Albuquerque1,3

featuring FL-01 CY3-labeled 192-IgG (Poster)

157.4 SCHWANN CELLS CAN ENTER THE DEMYELINATED SPINAL CORD FROM DORSAL ROOTS VIA SCAR TISSUE.

G.Janni*1; L.Jasmin2; P.T.Ohara3

featuring IT-14 CTB-SAP (Poster)

158.13 CAPSAICIN-SENSITIVE INHIBITORY PATHWAY IN RAT SPINAL CORD DORSAL HORN.

J.G.Gu1; T.Nakatsuka1; E.Tanaka*2; D.Takeda1; L.X.Jennifer1

featuring IT-10 IB4-SAP (Poster)

158.16 a, b-METHYLENE ATP SENSITIVE P2X RECEPTOR MEDIATED ENHANCEMENT OF GLUTAMATE RELEASE FROM THE CENTRAL TERMINALS OF A d PRIMARY AFFERENTS ONTO LAMINA V NEURONS IN RAT SPINAL CORD.

T.Nakatsuka*; D.Takeda; J.G.Gu

featuring IT-10 IB4-SAP (Poster)

175.10 SELECTIVE CHOLINERGIC DEAFFERENTATION AFFECTS GR mRNA EXPRESSION IN THE RAT BRAIN.

K.A.Helm*; J.S.Han; M.Gallagher

featuring IT-01 192-IgG-SAP (Poster)

202.5 INTERACTIONS BETWEEN PARTIAL CORTICAL CHOLINERGIC DEAFFERENTATION AND AGING ON SUSTAINED ATTENTION PERFORMANCE IN RATS.

J.A.Burk*; C.D.Herzog; M.C.Porter; J.Mahoney; J.P.Bruno; M.Sarter

featuring IT-01 192-IgG-SAP (Poster)

224.13 NK1-EXPRESSING NEURONS CRITICAL FOR MORPHINE REWARD BEHAVIORS IN MICE: c-Fos EXPRESSION AND ABLATION OF NK1-EXPRESSING NEURONS.

C.A.Gadd1; P.Murtra1,2; C.N.Hall1; M.Gana1; M.J.Webber1; C.De Felipe2; S.P.Hunt1

featuring IT-07 SP-SAP (Poster)

243.2 CENTRAL ORIGIN OF ATAXIC BREATHING AFTER LESION OF PREB&OumlTZINGER COMPLEX (PREB&OumlTC) NEUROKININ 1 RECEPTOR EXPRESSING (NK1R+) NEURONS.

W.A.Janczewski*; P.A.Gray; J.L.Feldman

featuring IT-07 SP-SAP (Slide)

254.1 LONG-TERM PLASTIC CHANGES IN GALANIN INNERVATION IN RAT BASAL FOREBRAIN.

I.Hartonian; S.de Lacalle*

featuring IT-01 192-IgG-SAP (Poster)

281.11 DOSE-DEPENDENT EFFECTS OF INTRATHECAL SUBSTANCE P-SAPORIN AND SSP-SAPORIN.

R.G.Wiley*1,2,3; R.H.Kline, IV1; D.A.Lappi4

featuring IT-11 SSP-SAP (Poster)

309.10 A NOVEL METHOD FOR LOCALIZED SYMPATHETIC NERVOUS SYSTEM DENERVATION OF PERIPHERAL TISSUE USING GUANETHIDINE.

T.J.Bartness*; G.E.Demas

featuring IT-03 Anti-DBH-SAP (Poster)

312.12 ESTROGEN ENHANCEMENT OF LEARNING REQUIRES INTACT BASAL FOREBRAIN CHOLINERGIC NEURONS.

R.B.Gibbs*

featuring IT-01 192-IgG-SAP (Poster)

313.13 CHOLINERGIC LESIONS OF THE THALAMIC RETICULAR NUCLEUS USING 192-IGG-SAPORIN.

D.S.Tait; M.Latimer; W.Woodson; V.J.Brown; BNASFN

featuring IT-01 192-IgG-SAP (Poster)

313.14 ENRICHED HOUSING, RETICULAR THALAMIC NUCLEUS AND NUCLEUS BASALIS: MEDIATORS OF ATTENTION AND LEARNING?

K.M.Sauro; M.Sweeney; M.J.Saari*

featuring IT-01 192-IgG-SAP (Poster)

313.2 VISUAL ORIENTING RESPONSE AND THE NUCLEUS BASALIS OF MEYNERT.

M.Isaac*; J.M.Pearce; J.L.Muir

featuring IT-01 192-IgG-SAP (Poster)

313.3 THE EFFECTS OF CORTICAL CHOLINERGIC DEPLETION ON THE PERFORMANCE OF ADULT RATS IN AN APPETITIVE-TO-AVERSIVE TRANSFER TASK.

J.A.Schultz*1; A.E.Butt2; C.L.George1; P.E.Garraghty1

featuring IT-01 192-IgG-SAP (Poster)

313.4 EFFECT OF CHLORDIAZEPOXIDE INFUSIONS INTO THE BASAL FOREBRAIN ON MEDIAL PREFRONTAL NEURAL ACTIVITY OF RATS DURING SUSTAINED VISUAL ATTENTION.

M.M.Yurrita1,2; B.Givens*1,2

featuring IT-01 192-IgG-SAP (Poster)

313.7 BASAL FOREBRAIN CHOLINERGIC AND GABAergic NEURONS MEDIATE DIFFERENT ASPECTS OF SUSTAINED ATTENTION PERFORMANCE IN RATS.

M.Sarter*; J.A.Burk; A.Graf; J.Russell; J.P.Bruno

featuring IT-01 192-IgG-SAP (Poster)

314.14 CHOLINERGIC AND NONCHOLINERGIC SEPTAL NEURONS MODULATE STRATEGY SELECTION IN PLACE LEARNING.

J.F.Cahill; M.G.Baxter*

featuring IT-01 192-IgG-SAP (Poster)

314.15 ENVIRONMENT-SPATIAL CONDITIONAL LEARNING: CONTRIBUTION OF MEDIAL SEPTAL CHOLINERGIC NEURONS.

O.Jackson*; E.F.Firoz; A.M.Janisiewicz; M.G.Baxter

featuring IT-01 192-IgG-SAP (Poster)

314.16 EFFECTS OF BASAL FOREBRAIN CHOLINERGIC LESIONS ON SPATIAL LEARNING IN MALE AND FEMALE RATS.

J.S.Rodefer*; Z.Jonasson; J.F.Cahill; R.E.Tobey; M.G.Baxter

featuring IT-01 192-IgG-SAP (Poster)

314.17 192 IGG SAPORIN LESIONS OF THE NUCLEUS BASALIS MAGNOCELLULARIS IMPAIR WORKING BUT NOT REFERENCE MEMORY IN A DELAYED NON-MATCH-TO-POSITION Y-MAZE TASK.

A.E.Butt*; M.M.Noble; H.Barrett; S.Brinegar; A.Hixon; B.Kester; D.Levey; T.Rea; M.Ryan; S.Schulze; L.Vogel

featuring IT-01 192-IgG-SAP (Poster)

314.18 THE ROLE OF THE CHOLINERGIC BASAL FOREBRAIN IN LEARNING, MEMORY AND REWARD EXPECTANCIES.

L.M.Savage*1; R.Buzzette1; D.Ramirez1

featuring IT-01 192-IgG-SAP (Poster)

376.5 NICOTINE ENHANCES N-METHYL-D-ASPARTATE RECEPTOR RESPONSES AND FACILITATES LONG-TERM POTENTIATION IN THE HIPPOCAMPUS FROM RATS WITH CHOLINERGIC LESIONS.

N.Hamaue*; Y.Yamazaki; H.Ohmori; K.Sumikawa

featuring IT-01 192-IgG-SAP (Poster)

409.6 NORADRENERGIC INPUTS TO THE PARAVENTRICULAR NUCLEUS (PVN) IS INVOLVED IN ESTROGEN RECEPTOR a EXPRESSION IN THE PVN OF 48-H FASTED AND 2DG-INJECTED FEMALE RATS.

M.A.Estacio; H.Tsukamura; B.A.Reyes; K.I.Maeda*

featuring IT-03 Anti-DBH-SAP (Poster)

410.7 HYPOCRETIN-SAPORIN (HCRT-SAP) As A TOOL TO EXAMINE HYPOCRETIN FUNCTION.

D.Gerashchenko1; M.D.Kohls2; M.A.Greco1; N.S.Waleh3; R.Salin-Pascual4; T.S.Kilduff3; D.A.Lappi2; P.J.Shiromani*1

featuring IT-20 Orexin-SAP (Poster)

410.8 LIGHT- AND FOOD-ENTRAINED CIRCADIAN RHYTHMS IN RATS WITH NEUROTOXIC LESIONS OF HYPOCRETIN CELLS.

R.E.Mistlberger*1; M.C.Antle1; M.Jones1; T.S.Kilduff2

featuring IT-20 Orexin-SAP (Poster)

410.9 HYPOCRETIN B-SAPORIN LESIONS OF THE BRAINSTEM INCREASE REM SLEEP AT NIGHT.

C.A.Blanco-Centurion*1; R.J.Salin-Pascual2; D.Gerashchenko1; M.A.Greco1; P.J.Shiromani1

featuring IT-20 Orexin-SAP (Poster)

418.7 MAZE STRATEGY IN RATS WITH GABAergic OR CHOLINERGIC LESIONS OF MEDIAL SEPTUM.

R.M.Yoder*1; S.A.Reuss1; K.C.Pang1

featuring IT-01 192-IgG-SAP (Poster)

426.8 SELECTIVE NEONATAL NEUROCHEMICAL LESIONS PERSIST INTO OLD AGE AND CAUSE ALZHEIMER-LIKE PATHOLOGY.

M.de Butte; T.Fortin; N.Sherren; B.A.Pappas*

featuring IT-01 192-IgG-SAP (Poster)

466.7 IMMUNOLESIONING OF BRAINSTEM DBH NEURONS ON THE MATING-INDUCED LH AND PROLACTIN SURGE IN THE RABBIT.

K.Pau*

featuring IT-03 Anti-DBH-SAP (Slide)

508.10 DERMORPHIN-SAPORIN CONJUGATE RELIEVES INFLAMMATORY PAIN AFTER PERIPHERAL APPLICATION.

J.Palecek*; V.Paleckova; W.D.Willis

featuring IT-12 Dermorphin-SAP (Poster)

522.21 LOSS OF HISTAMINERGIC NEURONS DOES NOT PRODUCE HYPERSOMNOLENCE.

T.C.Chou*1; D.Gerashchenko2; C.B.Saper1,3; P.J.Shiromani2

featuring IT-20 Orexin-SAP (Poster)

523.12 EFFECTS OF 192-SAPORIN LESION OF THE BASAL FOREBRAIN ON SLEEP HOMEOSTASIS AND ADENOSINE RECEPTOR (A1) mRNA LEVELS.

M.A.Greco*1; R.Salin-Pascual2; D.Gerashchenko1; C.Blanco-Centurion1; P.J.Shiromani1

featuring IT-01 192-IgG-SAP (Poster)

533.16 BASAL FOREBRAIN CHOLINERGIC SYSTEM: CORTICAL ACTIVATION, SLEEP/WAKING EEG AND EVOKED POTENTIALS.

R.Shafi; G.G.Berntson*; M.Sarter; T.Saurer; M.Spino

featuring IT-01 192-IgG-SAP (Poster)

534.13 LOW DOSE 192 IGG-SAPORIN SELECTIVELY DESTROYS BASAL FOREBRAIN CHOLINERGIC NEURONS AND IMPAIRS ACQUISITION OF A SPATIAL MEMORY TASK.

N.J.Zambon1; R.Nagle1; V.Pokala1; R.B.Gibbs2; D.A.Johnson*1

featuring IT-01 192-IgG-SAP (Poster)

539.5 BEHAVIOURAL AND NEUROCHEMICAL CHANGES ASSOCIATED WITH SINGLE AND COMBINED ACETYLCHOLINE AND DOPAMINE LESIONS IN NEONATAL RATS.

N.Sherren*; B.A.Pappas

featuring IT-01 192-IgG-SAP (Poster)

541.14 NEONATAL CHOLINERGIC LESIONS ALTER REACTIVITY TO A GABAergic AGONIST IN 18-DAY-OLD RATS.

L.Ricceri1; M.L.Scattoni1; G.Calamandrei1

featuring IT-01 192-IgG-SAP (Poster)

549.16 a-1 ADRENERGIC AGONIST EFFECT ON CHOLINERGIC MUSCARINIC RECEPTORS.

L.E.Harrell*1,2; K.Kolasa1; D.S.Parsons1; K.Conger2

featuring IT-01 192-IgG-SAP (Poster)

549.17 a-1 ADRENERGIC ANTAGONIST EFFECT ON CHOLINERGIC MUSCARINIC RECEPTORS.

K.Kolasa*1,2; L.E.Harrell1,2; D.S.Parsons1,2; K.Conger2

featuring IT-01 192-IgG-SAP (Poster)

573.1 DESTRUCTION BY SP-SAP OF RAT RETROTRAPEZOID NUCLEUS (RTN) NEURONS EXPRESSING THE NEUROKININ 1 RECEPTOR (NK1R) DECREASES BREATHING AT REST AND IN RESPONSE TO HYPERCAPNIA.

E.E.Nattie*; A.Li

featuring IT-07 SP-SAP (Slide)

599.7 SELECTIVE CHOLINERGIC DENERVATION INHIBITS EXPRESSION OF LONG-TERM POTENTIATION IN THE ADULT BUT NOT INFANT RAT HIPPOCAMPUS.

Y.Motooka1; T.Kondoh*1; T.Nomura2; N.Tamaki1; T.Nishizaki2

featuring IT-01 192-IgG-SAP (Poster)

621.2 SOUND SEQUENCE DISCRIMINATION REQUIRES CHOLINERGIC INPUTS AND SUPPRESSION OF M-CURRENTS IN THE RAT AUDITORY CORTEX.

M.Kudoh*; K.Seki; S.Watanabe; K.Shibuki

featuring IT-01 192-IgG-SAP (Poster)

626.14 IMMUNOLESIONING OF IDENTIFIED MOTONEURON POOLS FOLLOWING INTRAMUSCULAR INJECTION OF THE IMMUNOTOXIN, 192-IGG-SAPORIN, IN NEONATAL RATS.

W.E.Peterson1; L.M.Jordan*1; R.M.Brownstone2

featuring FL-01 CY3-labeled 192-IgG (Poster)

633.4 DL-HOMOCYSTEIC (DLH)-INDUCED TACHYPNEA IS ELIMINATED BY ABLATION OF NEUROKININ-1 RECEPTOR IMMUNOREACTIVE (NK1R-Ir) NEURONS OF THE PREB&OumlTZINGER COMPLEX (PREB&OumlTC).

H.Wang*; P.G.Guyenet

featuring IT-07 SP-SAP (Poster)

635.21 SELECTIVE IMMUNOTOXIN LESIONS OF HINDBRAIN NOREPINEPHRINE/EPINEPHRINE (Ne/E) NEURONS IMPAIR FEEDING AND CORTICOSTERONE RESPONSES AND FOS-IMMUNOREACTIVITY IN HYPOTHALAMIC SITES DURING INSULIN-INDUCED HYPOGLYCEMIA (IIH).

N.M.Sanders*; T.T.Dinh; C.Pedrow; S.Ritter

featuring IT-03 Anti-DBH-SAP (Poster)

771.3 MONOAMINE MODULATION OF SPINAL REFLEX EXCITABILITY OF THE LOWER LIMB IN THE RAT: INTRATHECAL INFUSION (I.T.) OF ANTI-DBH SAPORIN TOXIN – TIME COURSE FOR BEHAVIOR.

P.Bose*1; D.C.Wang1; R.Parmer1; R.G.Wiley2; F.J.Thompson1

featuring IT-03 Anti-DBH-SAP (Poster)

771.5 MONOAMINE MODULATION OF SPINAL REFLEX EXCITABILITY OF THE LOWER LIMB IN THE RAT: INTRATHECAL (I.T.) INFUSION OF ANTI-DBH SAPORIN TOXIN – TIME COURSE FOR NEUROPHYSIOLOGY.

D.C.Wang*1; P.Bose1; R.Parmer1; R.G.Wiley2; F.J.Thompson1

featuring IT-03 Anti-DBH-SAP (Poster)

803.6 BCL-2 IMPROVES SURVIVAL OF LESIONED CHOLINERGIC NEURONS.

K.Y.Lee; R.Leos; T.B.Borowski*; S.de Lacalle

featuring IT-01 192-IgG-SAP (Poster)

814.9 A MONOCLONAL ANTIBODY TO AN EXTRACELLULAR DOMAIN OF THE SEROTONIN TRANSPORTER: CHARACTERIZATION AND TARGETING PROPERTIES.

M.D.Kohls1; K.A.Majer1; B.J.Russell1; Q.Han2; R.D.Blakely2; D.A.Lappi*1

featuring AB-N09 Antibody to SERT (Poster)

947.1 SELECTIVE IMMUNOTOXIN LESION OF SPINALLY PROJECTING NOREPINEPRHINE AND EPINEPHRINE (Ne/E) NEURONS IMPAIRS THE GLUCAGON RESPONSE TO 2-DEOXY-D-GLUCOSE (2DG).

T.T.Dinh*; N.M.Sanders; C.Pedrow; S.Ritter

featuring IT-03 Anti-DBH-SAP (Poster)

947.2 IMMUNOTOXIN LESION OF CATECHOLAMINERGIC NEURONS INNERVATING THE MEDIAL HYPOTHALAMUS ELEVATES BASAL EXPRESSION OF AND ATTENUATES GLUCOPRIVAATION-INDUCED INCREASES IN AGOUTI GENE RELATED PROTEIN (AGRP) mRNA.

G.S.Fraley*; T.T.Dinh; S.Ritter

featuring IT-03 Anti-DBH-SAP (Poster)

947.3 SELECTIVE IMMUNOTOXIN LESION OF HYPOTHALAMICALLY-PROJECTING NOREPINEPHRINE/EPINEPHRINE (Ne/E) NEURONS IMPAIRS THE GLUCOCORTICOID RESPONSE TO GLUCOPRIVATION.

S.Ritter*; T.T.Dinh; N.M.Sanders; C.Pedrow

featuring IT-03 Anti-DBH-SAP (Poster)

948.2 HYPERPHAGIA AND OBESITY RESULTS FROM THE INJECTION OF THE IMMUNOTOXIN NEUROPEPTIDE Y (NPY)-SAPORIN (NPY-SAP) INTO THE PARAVENTRICULAR HYPOTHALAMUS (PVH) OF RATS.

K.Bugarith*; S.Ritter; T.Dinh

featuring NPY-SAP (Poster)

958.18 TARGETED LESIONS OF SUBSTANCE P RECEPTOR CELLS IN L3-4 LUMBAR SPINAL CORD SEVERELY IMPAIR MALE EJACULATORY BEHAVIOR.

W.A.Truitt*; L.A.Stanton; L.M.Coolen

featuring IT-11 SSP-SAP (Poster)