Abstracts from Society for Neuroscience (SFN) – New Orleans, LA | November 4-9, 2000

41.7 IMMUNOHISTOCHEMICAL DETECTION OF ALPHA-7 NICOTINIC RECEPTOR EXPRESSION BY TWO DISTINCT CELL TYPES IN THE DORSAL RAPHE AND LOCUS COERULEUS OF RAT.

R.S. Bitner*; A.L. Nikkel; M.W. Decker

featuring IT-03 Anti-DBH-SAP (Poster)

51.22 SENSORY TRAINING IMPROVES THE ABILITY TO PROCESS STIMULI IN BARREL CORTEX AFTER BASAL FOREBRAIN LESION.

O. Rahimi*; D. Tatham; S.L. Juliano

featuring IT-01 192-IgG-SAP (Poster)

77.13 LOCAL IMMUNOTOXIN TREATMENT PREVENTS TRANSNEURONAL LABELING OF THE INTERMEDIOLATERAL COLUMN; BUT NOT THE VENTRAL HORN; OF THE SPINAL CORD AFTER TRACER INJECTION INTO LUMBAR EPAXIAL MUSCLE.

D. Daniels1*; R.R. Miselis2;3; L.M. Flanagan-Cato1;3

featuring IT-03 Anti-DBH-SAP (Poster)

119.3 DEPLETION OF CHOLINERGIC AMACRINE CELLS DOES NOT PERTURB THE SEGREGATION OF ON AND OFF CONE BIPOLAR CELL PROJECTIONS.

E. Gunhan-Agar; P. Choudary; T.-E. Landerholm; L.-M.- Chalupa*

featuring CUSTOM (Poster)

205.8 CROSSED UNILATERAL LESIONS OF THE CHOLINERGIC BASAL FOREBRAIN (BY ME20.4IGG-SAPORIN) AND FORNIX FROM INFERIOR TEMPORAL CORTEX PRODUCE SEVERE LEARNING IMPAIRMENTS IN RHESUS MONKEYS.

A. Easton1*; R.M. Ridley2; H.F. Baker2; D. Gaffan1

featuring IT-15 ME20.4-SAP (Slide)

212.7 ROLE OF IB4-BINDING SENSORY NEURONS IN THE EFFECTS OF INTRADERMAL CAPSAICIN INJECTION.

L. Vulchanova1*; T.H. Olson1;2; R. Elde1;2; C.N. Honda1;2

featuring IT-10 IB4-SAP (Slide)

212.8 INTRATHECAL DERMORPHIN-SAPORIN DECREASES MORPHINE EFFECT IN HOTPLATE ALGESIA TESTING.

S.A. Miller1;2; D.A. Lappi3; R.G. Wiley1;2*

featuring IT-12 Dermorphin-SAP (Slide)

238.1 DISTRIBUTION OF MU-OPIOID RECEPTORS AND ACTIVATED G-PROTEINS IN RAT CINGULATE CORTEX AND ALTERATIONS FOLLOWING REMOVAL OF NORADRENERGIC AFFERENTS.

L.J. Vogt1;2*; L.J. Sim-Selley3; S.R. Childers2; R.G. Wiley4; B.A. Vogt1;2

featuring IT-03 Anti-DBH-SAP (Poster)

243.6 DERMORPHIN-SAPORIN TARGETS TONIC DESCENDING FACILITATION IN THE ROSTRAL VENTROMEDIAL MEDULLA TO BLOCK AND REVERSE NEUROPATHIC PAIN.

S.E. Burgess1; T.W. Vanderah1; P.W. Mantyh2; T.P. Malan; Jr.1; M.H. Ossipov1; D. Lappi3; J. Lai1*; F. Porreca1

featuring IT-12 Dermorphin-SAP (Poster)

243.7 CHRONIC NORADRENERGIC SPINAL DENERVATION IN RATS DOES NOT PRODUCE LONG-TERM HYPERALGESIA.

L. Jasmin1*; P. Arsenault3; P.T. Ohara2; S. Marchand3

featuring IT-03 Anti-DBH-SAP (Poster)

247.10 ALTERED OPERANT AND REFLEX RESPONSES TO NOXIOUS HEAT IN RATS WITH CENTRAL NORADRENERGIC LESIONS USING ANTIDbH-SAPORIN.

C.J. Vierck1*; P.M. Belford3; M.A. Iqbal3; C. Camara3; R.H. Kline3; D.A. Lappi2; R.G. Wiley3

featuring IT-03 Anti-DBH-SAP (Poster)

310.2 INTRATHECAL INJECTIONS OF SAPORIN CONJUGATED SUBSTANCE-P ALTER THE DEVELOPMENT OF RENAL HYPERTENSION.

J. Ciriello*; M.P. Rosas-Arellano; L.P. Solano-Flores

featuring IT-07 SP-SAP (Slide)

310.7 REGULATION OF SYMPATHETIC VASOMOTOR TONE AND ARTERIAL PRESSURE BY THE ROSTRAL VENTROLATERAL MEDULLA AFTER ELIMINATION OF C1 NEURONS IN RAT.

A.M. Schreihofer*; R.L. Stornetta; P.G. Guyenet

featuring IT-03 Anti-DBH-SAP (Slide)

354.7 DIFFERENTIAL INPUT TO A NOCICEPTIVE SPECIFIC REFLEX BY TRKA-POSITIVE AND TRKA-NEGATIVE SMALL DIAMETER DRG AFFERENTS.

J.C. Petruska1*; R.D. Johnson1;2

featuring IT-01 192-IgG-SAP (Poster)

388.16 FEEDBACK HPA AXIS TO STRESS IS IMPAIRED IN RATS WITH SELECTIVE REMOVAL OF HIPPOCAMPAL CHOLINERGIC INPUT.

J.S. Han*; J.L. Bizon; H.J. Chun; C.E. Maus; M. Gallagher

featuring IT-01 192-IgG-SAP (Poster)

389.13 FOCAL HIPPOCAMPAL HYPEREXCITABILITY AFTER FOCAL INTERNEURON ABLATION IN THE RAT BY SUBSTANCE P-SAPORIN.

J.L. Martin; R.S. Sloviter*

featuring IT-11 SSP-SAP (Poster)

502.8 ANTI-DbH-SAPORIN INJECTION INTO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS SELECTIVELY ABOLISHES 2DG-INDUCED FEEDING WITHOUT CAUSING NONSPECIFIC TISSUE DESTRUCTION.

S. Ritter*; T.T. Dinh; K. Bugarith

featuring IT-03 Anti-DBH-SAP (Slide)

507.2 ELIMINATION OF MICROGLIA SUGGESTS THEIR INVOLVEMENT IN NEURONAL PLASTICITY.

M.M. Siddiq1,2; S.E. Tsirka2,3*

featuring IT-06 MAC-1-SAP (Poster)

516.8 SCHWANN CELLS ARE REMOVED FROM THE RAT SPINAL CORD AFTER EFFECTING RECOVERY FROM PARAPLEGIA.

G. Janni1*; T. Moallem1; D.A. Lappi3; P.T. Ohara1; L. Jasmin2

featuring IT-14 CTB-SAP (Poster)

563.1 THE BEHAVIORAL AND NEUROCHEMICAL EFFECTS OF ACUTE AND INCREMENTAL CHOLINERGIC LESIONS ON VISUAL ATTENTION DURING A 5-CHOICE SERIAL REACTION TIME TASK.

J.A. McGaughy*; J.W. Dalley; T.W. Robbins; B.J. Everitt

featuring IT-01 192-IgG-SAP (Poster)

563.13 A SPECIFIC CHOLINERGIC IMMUNOTOXIN IN MICE.

J.E. Berger-Sweeney1; S.L. Murg2; M.G. Baxter2; N.A. Stearns1; D.A. Lappi3*

featuring IT-16 mu p75-Saporin (Poster)

563.2 COMBINED CHOLINERGIC DENERVATION OF THE HIPPOCAMPUS AND POSTERIOR CINGULATE CORTEX FAILS TO IMPAIR WORKING MEMORY PERFORMANCE BUT MAY PRODUCE DEFICITS IN BEHAVIOURAL FLEXIBILITY IN THE RAT.

B.D. Winters1;2*; S.B. Dunnett1;2

featuring IT-01 192-IgG-SAP (Poster)

563.3 SELECTIVE DESTRUCTION OF BASAL FOREBRAIN CHOLINERGIC NEURONS IMPAIRS ACQUISITION OF A SPATIAL MEMORY TASK.

D.A. Johnson1*; N.J. Zambon1; R.B. Gibbs2

featuring IT-01 192-IgG-SAP (Poster)

563.4 PRESERVATION OF REACTIVITY TO SPATIAL NOVELTY IN ADULT RATS AFTER SPECIFIC BASAL FOREBRAIN 192 IGG-SAPORIN LESIONS.

L. Ricceri1; M.G. Baxter2; K.M. Frick3; J. Berger-Sweeney3

featuring IT-01 192-IgG-SAP (Poster)

563.5 A TEST OF NEGATIVE PATTERNING REVEALS SELECTIVE IMPAIRMENT IN CONFIGURAL ASSOCIATION LEARNING IN RATS WITH 192 IGG-SAPORIN LESIONS OF THE NUCLEUS BASALIS MAGNOCELLULARIS.

A.E. Butt*; K. Allen; K. Arthur; C. Cole; S. Cook; A. Gerth; M. Hoichi; C. Long; M. Noble; T. Rea; J. Rogers

featuring IT-01 192-IgG-SAP (Poster)

563.6 THE ROLE OF MEDIAL SEPTAL CHOLINERGIC AND GABAERGIC NEURONS IN SOCIAL MEMORY.

A.J. Secor1;2; J. Bishop1;2; K.C.H. Pang1;2*

featuring IT-01 192-IgG-SAP (Poster)

563.7 192 IGG-SAPORIN IMMUNOLESIONING CAUSES MARKED FACILITATION OF DOPAMINE-MEDIATED LOCOMOTOR ACTIVITY IN ADULT RATS.

A. Mattsson; S.O. Ögren; L. Olson*

featuring IT-01 192-IgG-SAP (Poster)

563.8 CONTRIBUTION OF THE CHOLINERGIC BASAL FOREBRAIN TO PROACTIVE INTERFERENCE BETWEEN STORED ODOR MEMORIES DURING ASSOCIATIVE LEARNING IN RATS: 192 IGG-SAPORIN IMMUNOTOXIC LESIONS.

E. De Rosa1*; M.E. Hasselmo2; M.G. Baxter1

featuring IT-01 192-IgG-SAP (Poster)

566.17 DBH-SAPORIN LESIONS THE LOCUS COERULEUS; BUT DOES NOT PRODUCE CATAPLEXY OR ABNORMAL REM SLEEP TRIGGERING.

C.A. Blanco-Centurion1*; R. Salin-Pascual1; D. Gerashchenko1; M.A. Greco1; D.A. Lappi2; T.S. Kilduff3; P.J. Shiromani1

featuring IT-03 Anti-DBH-SAP (Poster)

566.27 OREXIN-B CONJUGATED TO SAPORIN LESIONS LH AND TMN NEURONS AND PRODUCES NARCOLEPTIC-LIKE SLEEP IN RATS.

D. Gerashchenko1; M.-A. Greco1; R. Salin-Pascual1; T.S. Kilduff2; D.A. Lappi3; P.J. Shiromani1*

featuring IT-20 Orexin-SAP (Poster)

571.2 REDUCED ANXIETY RELATED BEHAVIOR FOLLOWING ABLATION OF AMYGDALA NEURONS EXPRESSING SUBSTANCE P RECEPTOR.

S.D. Rogers1; J.L. Salak-Johnson1;2*; M.J. Schwei1; J.D. Pomonis1; P.W. Mantyh1

featuring IT-07 SP-SAP (Poster)

633.18 CONTRIBUTION OF IB4-POSITIVE SENSORY NEURONS TO NGF-INDUCED HYPERALGESIA IN THE RAT.

J.W. Tarpley; W.J. Martin*; B.S. Baldwin; M.J. Forrest; D.E. MacIntyre

featuring IT-10 IB4-SAP (Poster)

635.13 RESPONSES OF SPINAL DORSAL HORN NEURONS TO CAPSAICIN FOLLOWING INTRATHECAL PRETREATMENT WITH SUBSTANCE P-SAPORIN TOXIN.

S.G. Khasabov1; S.D. Rogers1; P.W. Mantyh1;3; D.A. Simone1;2*

featuring IT-07 SP-SAP (Poster)

639.8 INTRACORTICAL INJECTION OF DBH-SAPORIN TARGETS NORADRENERGIC AXONS IN THE MEDIAL PREFRONTAL CORTEX OF THE RAT.

M.S. Mazei1; R.G. Wiley2; A.Y. Deutch1*

featuring IT-03 Anti-DBH-SAP (Poster)

722.6 NGF-INDUCED RAPID FUNCTIONAL PLASTICITY IN THE ADULT RAT SOMATOSENSORY CORTEX IS MEDIATED BY FIBERS ORIGINATING IN THE BASAL FOREBRAIN CHOLINERGIC SYSTEM.

N. Prakash1;2*; S.C. Cohen-Cory3; R.D. Frostig1

featuring IT-01 192-IgG-SAP (Poster)

733.4 ANATOMICAL EVIDENCE FOR GLIAL ACTIVATION AFTER INTRATHECAL LUMBOSACRAL HIV-1 GLYCOPROTEIN; GP120-INDUCED ALLODYNIA.

A. Holguin1*; C.B. Armstrong1; C.M. Twining1; E.D. Milligan1; M.K. Hansen1; M. McGorry1; K.A. O’Connor1; N. Quan2; D. Martin3; D.A. Lappi4; S.F. Maier1; L.R. Watkins1

featuring IT-06 MAC-1-SAP (Poster)

733.9 PREVENTION AND TREATMENT OF A SPONTANEOUS PAIN-LIKE BEHAVIOR FOLLOWING EXCITOTOXIC SPINAL CORD INJURY (SCI) BY ABLATION OF NEURONS EXPRESSING THE SUBSTANCE P RECEPTOR.

R.P. Yezierski1*; C.G. Yu1; R.G. Wiley2

featuring IT-11 SSP-SAP (Poster)

837.10 EFFECTS OF INTRA-BASALIS INFUSION OF D-CYCLOSERINE UPON SUSTAINED ATTENTION PERFORMANCE IN RATS.

M. Sarter*; J. Turchi

featuring IT-01 192-IgG-SAP (Poster)

837.3 NUCLEUS BASALIS MAGNOCELLULARIS AND ENRICHED HOUSING: PARTNERS IN NEURAL PATTERNS OF ATTENTION?

C. Westhead; R.K. Saari; P. Morrison; P.T. Williams; M.J. Saari*

featuring IT-01 192-IgG-SAP (Poster)

837.6 ATTENTIONAL DEMAND-RELATED ALTERATIONS IN MEDIAL PREFRONTAL NEURAL ACTIVITY OF AGED RATS DURING SUSTAINED VISUAL ATTENTION.

T.M. Gill*; M.M. Yurrita; B. Givens

featuring IT-01 192-IgG-SAP (Poster)