Targeting Trends

Targeting Tools: Anti-CRH/CRF

Anti-CRH/CRF, Cat. #AB-02 Corticotropin-releasing hormone/factor (CRH/CRF) is the principal neuropeptide involved in regulating the stress response. It stimulates ACTH release from the pituitary gland. When centrally administered to animals it produces somatic changes analogous to those seen in both depression and anxiety. In humans, it is capable of reproducing the hormonal changes which are characteristically […]

Targeting Tools: Anti-CRH/CRF Read More »

Targeting Tools: Anti-Pseudomonas aeruginosa

Anti-Pseudomonas aeruginosa, Cat. #AB-T057 Pseudomonas aeruginosa is a Gram-negative bacterium that causes many infections, particularly in people with cystic fibrosis, burn victims, individuals with cancer and others who are immunosuppressed. This bacterium is studied by scientists not only because of its ability to cause disease and resist antibiotics, but also its metabolic capability and environmental

Targeting Tools: Anti-Pseudomonas aeruginosa Read More »

Cover Article: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain

Contributed by Neelima Chauhan, Dept Anesthes/Anat & Cell Bio, Univ Illinois-Chicago;J. Brown VA Med Ctr Chicago, Chicago, IL and winner of the 2006 SfN Poster Award for work using ATS products. Today’s Alzheimer’s disease (AD) research lacks a “complete” model that would represent both plaque and tangle pathology together with correlative memory deficits. The currently

Cover Article: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain Read More »

Cover Article: Basomedial Hypothalamic Injections of Neuropeptide Y Conjugated to Saporin Selectively Disrupt Hypothalamic Controls of Food Intake

This article is a summary of data presented in reference #1. Figures 1-4 are taken from that article. This work was funded by NS045520 and DK40498 to S. Ritter. Neuropeptide Y (NPY) conjugated to saporin (SAP), a ribosomal toxin, is a compound designed to selectively target and lesion NPY receptor-expressing cells. We conducted competitive binding

Cover Article: Basomedial Hypothalamic Injections of Neuropeptide Y Conjugated to Saporin Selectively Disrupt Hypothalamic Controls of Food Intake Read More »

Cover Article: Safety and Efficacy of Substance P-SAP

contributed by Jeffrey W. Allen, Ph.D.The author is currently a Senior Scientist in Emerging Therapies at Medtronic Neurological located in Minneapolis, MN.There is no association, financial or otherwise, between Medtronic, Inc. and Advanced Targeting Systems. Substance P-saporin (SP-SAP, Cat. #IT-07) is a targeted neurotoxin that selectively lesions cells containing the Neurokinin-1 (NK-1) receptor. Previous studies

Cover Article: Safety and Efficacy of Substance P-SAP Read More »

Targeting Tools: Fluorescent Conjugates

Antibodies conjugated to fluorescent dyes are vibrant and vital tools at a scientist’s disposal. ATS currently has six fluorescent conjugates in our catalog: Cy3-labeled 192-IgG (Cat. #AB-N43FL3), FITC-labeled Anti-Saporin (Cat. #AB-15APFL), Alexa 488-labeled 192-IgG (Cat. #AB-N43FLA), FITC-labeled Goat anti-rabbit IgG (Cat. #FL-04), Cy3- labeled anti-NGFr (Cat. #AB-N01APFL3), and Cy5-labeled anti- NGFr (Cat. #AB-N01APFL5). ATS also

Targeting Tools: Fluorescent Conjugates Read More »

Shopping Cart
Scroll to Top