Abstracts from Society for Neuroscience (SFN) November 14-17, 2010 • San Diego, CA

32.14/D20 Early post-natal cholinergic lesion impairs normal development and maturation of the motor cortex in rats

D Ramanathan, J M Conner, A A Anilkumar, M H Tuszynski

featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov. 13, 2:00 pm – 3:00 pm)

33.1/E1 Subplate neurons promote the formation of barrels within rat primary somatosensory cortex

A Sheikh, P O Kanold

featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov. 13, 2:00 pm – 3:00 pm)

99.27/KKK13 Cholinergic innervation of the hippocampus is not neccesary for episodic memory, but is required for context-place learning in rats

A Easton, D Phil, A Fitchett, M J Eacott, M G Baxter

featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov. 13, 3:00 pm – 4:00 pm)

145.5/H6 Decrease of Arc protein expression and delay of memory acquisition by immunolesion

D Jeong, D Lee, J Chang

featuring IT-01 192-IgG-SAP (Poster; Sunday, Nov. 14, 8:00 am – 9:00 am)

349.8/J12 The effects of neonatal cholinergic lesion on age-related changes in behaviour, neurogenesis and CA1 pyramidal cell morphology

K E Rennie, M Frechette, B A Pappas

featuring IT-01 192-IgG-SAP (Poster; Monday, Nov. 15, 11:00 am -12:00 pm)

506.12/LLL52 Mesolimbic-basal forebrain circuitry mediating the motivational activation of attention

M M St Peters, J P Bruno, M Sarter

featuring IT-01 192-IgG-SAP (Poster; Monday, Nov. 15, 4:00 pm – 5:00 pm )

506.9/LLL49 Novel object recognition and social interaction in rats lacking cortical cholinergic innervation; comparing manual and digital video tracking systems

S T Savage, L Olson, A Mattsson

featuring IT-01 192-IgG-SAP (Poster; Monday, Nov. 15, 1:00 pm – 2:00 pm)

535.8 Cholinergic modulation of both visual and olfactory attention with the five-choice serial reaction time test

V Ljubojevic,, P Luu, E De Rosa

featuring IT-01 192-IgG-SAP (Nanosymposium; Tuesday, Nov. 16, 9:45 am -10:00 am )

611.16/MMM67 Effects of basal forebrain cholinergic lesions and estradiol on relative levels of estrogen receptor mRNAs in the rat forebrain

R Hammond, A Shinde, R B Gibbs

featuring IT-01 192-IgG-SAP (Poster; Tuesday, Nov. 16, 11:00 am -12:00 pm)

710.23/NNN23 Donepezil enhances effects of estradiol on DMP acquisition in rats with partial loss of septal cholinergic neurons

R B Gibbs, A M Chipman, D Nelson

featuring IT-01 192-IgG-SAP ( Halls B-H; Tuesday, Nov. 16, 3:00 pm – 4:00 pm )

856.27/I33 Molsidomine promotes the recovery of cognitive deficit induced by 192 IgG saporin in rats

M A Hernandez, M Hernández-Melesio, D Gonzalez-Ezquivel, L Quevedo-Corona, M Jiménez-Cataño, M Santoyo-Pérez, C Rios-Castañeda, F Pérez-Severiano

featuring IT-01 192-IgG-SAP ( Halls B-H; Wednesday, Nov. 17, 3:00 pm – 4:00 pm )

90.7/FFF13 Anxiety-like behavior in the elevated plus maze (EPMZ) depends on noradrenergic (NA) inputs to the anterolateral bed nucleus of the stria terminalis (alBST) in rats

H Zheng, L M Rinaman

featuring IT-03 Anti-DBH-SAP (Poster; Saturday, Nov. 13, 3:00 pm – 4:00 pm)

157.20/R1 Time- and dose-response of 6-hydroxydopamine on locus coeruleus noradrenegric neurons in c57bl/6 mice

P Szot, A Franklin, S White, M Raskind

featuring IT-03 Anti-DBH-SAP (Poster; Sunday, Nov. 14, 11:00 am – 12:00 pm)

392.14/III1 Hindbrain catecholamine neurons are required for rapid switching of metabolic substrate utilization during glucoprivation

A-J Li, Q Wang, T T Dinh, S Ritter

featuring IT-03 Anti-DBH-SAP (Poster; Monday, Nov. 15, 9:00 am -10:00 am)

833.3 Defining the role of norepinephrine in cannabinoid-induced aversion and anxiety

A F Carvalho, E Van Bockstaele

featuring IT-03 Anti-DBH-SAP (Nanosymposium; Wednesday, Nov. 17, 1:30 pm – 1:45 pm )

694.11/HHH34 Patterning of somatosympathetic reflexes: Identification of distinct bulbospinal sympathoexcitatory RVLM projections by conduction velocity and catecholamine phenotype

P G Burke, J Neale, W S Korim, S Mcmullan, P M Pilowsky, A K Goodchild

featuring IT-03 Anti-DBH-SAP; IT-18 Mouse IgG-SAP (Poster; Tuesday, Nov. 16, 3:00 pm – 4:00 pm)

81.21/VV19 Carageenan evoked P-Akt in deep dorsal horn neurons is prevented by loss of neurokinin1 positive neurons in superficial dorsal horn

L S Sorkin, J-I Choi, F J Koehrn

featuring IT-11 SSP-SAP (Poster; Saturday, Nov. 13, 1:00 pm – 2:00 pm)

99.26/KKK12 The role of GABA-ergic interneurons in CA1 and dentate gyrus for sequence learning

C S Weeden, A M Morris, C A Rossi, J M Roberts, R P Kesner,

featuring IT-11 SSP-SAP (Poster; Saturday, Nov. 13, 2:00 pm – 3:00 pm)

678.15/QQ2 NK-1 Receptors in the RVM: Involvement in hyperalgesia produced by naloxone but not in morphine analgesia

S G Khasabov, P M Fliss, A S Rao, D A Simone

featuring IT-11 SSP-SAP (Poster; Tuesday, Nov. 16, 3:00 pm – 4:00 pm )

811.1/LLL64 Evidence that focal hippocampal interneuron loss disrupts theta-rhythm activity in dorsal CA1

C A Rossi, M J Lehmkhule, R P Kesner, F E Dudek

featuring IT-11 SSP-SAP (Poster; Wednesday, Nov. 17, 8:00 am – 9:00 am)

585.5/XX19 Neuropeptide receptor co-expression in superficial dorsal horn: Effects of galanin-saporin, neuropeptide y-saporin and dermorphin-saporin

L L Lemons,, K Chatterjee, R G Wiley

featuring IT-12 Dermorphin-SAP; IT-34 Galanin-SAP; IT-28 NPY-SAP (Poster; Tuesday, Nov. 16, 8:00 am – 9:00 am )

585.1/XX15 Targeting inhibitory neurons in the superficial dorsal horn: Somatostatin-saporin

K Chatterjee, L L Lemons, R G Wiley

featuring IT-13 CRF-SAP; Custom Conjugate Somatostatin-SAP (Poster; Tuesday, Nov. 16, 8:00 am – 9:00 am )

259.19/W12 The recovery of locomotion after lumbar spinal cord motoneuron depletion is affected by the modulation of Sonic Hedgehog and Notch-1 pathways

R Gulino, M Gulisano

featuring IT-14 CTB-SAP (Poster; Sunday, Nov. 14, 3:00 pm – 4:00 pm)

331.5/B19 Functional cholinergic neurons from human embryonic stem cells

Y Liu, R Krencik, H Liu, L Ma, X Zhang, S-C Zhang

featuring IT-16 mu p75-SAP (Poster; Monday, Nov. 15, 8:00 am – 9:00 am)

856.15/I21 The effects of a combination of antioxidants and essential fatty acids as treatment for Alzheimer’s disease in the mu-p75 saporin-injected model

J J Matchynski, S A Lowrance, J Rossignol, N W Dekorver, N D Puckett, C A Pappas, K J Trainor, J L Delongchamp, J Radwan, J C Heldt, N D Dey, G L Dunbar

featuring IT-16 mu p75-SAP ( Halls B-H; Wednesday, Nov. 17, 3:00 pm – 4:00 pm )

856.8/I14 Krx-0501 reduces cognitive deficits in a saporin mouse model of Alzheimer’s disease

S A Lowrance, J J Matchynski, J Rossignol, N Dekorver, K Fink, P Salibi, G L Dunbar

featuring IT-16 mu p75-SAP ( Halls B-H; Wednesday, Nov. 17, 4:00 pm – 5:00 pm )

648.16/H17 The arcuate nucleus of the hypothalamus controls the circadian distribution of sleep and feeding

M F Wiater, S Mukherjee, T T Dinh, E Rooney, A-J Li, S M Simasko, S Ritter

featuring IT-28 NPY-SAP; IT-21 Blank-SAP (Poster; Tuesday, Nov. 16, 4:00 pm – 5:00 pm)

175.22/MM12 Decreasing abnormal nocifensive responses in the bilateral chronic constriction injury (bCCI) model of neuropathic pain: Effects of lumbar intrathecal CCK-saporin

S Datta, K Chatterjee, R Wiley

featuring IT-31 CCK-SAP (Halls B-H; Sunday, Nov. 14, 9:00 am – 10:00 am)

611.13/MMM64 Damage of GABAergic neurons in the medial septum-diagonal band (MSDB) reduces behaviorally-activated hippocampal acetylcholine efflux and impairs spatial working memory

J J Roland, K L Janke, L M Savage, R J Servatius, K C H Pang

featuring IT-32 GAT1-SAP (Poster; Tuesday, Nov. 16, 8:00 am – 9:00 am )

806.16/KKK21 Role of the septohippocampal GABAergic system in spatial orientation

J R Koppen, S S Winter, J L Cheatwood, D G Wallace

featuring IT-32 GAT1-SAP (Poster; Wednesday, Nov. 17, 11:00 am -12:00 pm)

811.3/LLL66 Do GAT1-saporin lesions of the medial septum damage GABAergic afferents to the medial septum?

M Gielow, J Roland, R J Servatius, K C H Pang

featuring IT-32 GAT1-SAP (Poster; Wednesday, Nov. 17, 10:00 am -11:00 am )

678.9/PP14 Morphine-induced pain hypersensitivity, but not opioid tolerance, depends on microglia-mediated alteration of Cl- homeostasis in spinal dorsal horn

F Ferrini,, T-A M Mattioli, L-E Lorenzo, A Godin, P W Wiseman, A Ribeiro-Da-Silva, C M Cahill, B Milne, Y De Koninck

featuring IT-33 Mac-1-SAP rat (Poster; Tuesday, Nov. 16, 1:00 pm – 2:00 pm )

300.28/KKK36 Lesioning of the ventrolateral preoptic nucleus alters isoflurane-induced hypnosis in a time-dependent fashion

J T Moore, H S Mccarren, S G Beck, M B Kelz

featuring IT-34 Galanin-SAP (Poster; Sunday, Nov. 14, 4:00 pm – 5:00 pm)

176.2/OO4 Gastrin-releasing peptide receptor in the spinal cord mediates mechanical allodynia following nerve injury

C Li, S Back, J Lee, S K Baek, H Na

featuring IT-40 Bombesin-SAP (Poster; Sunday, Nov. 14, 11:00 am -12:00 pm)

498.6/III29 Leptin-saporin lesion of hypothalamic arcuate neurons impairs circadian feeding rhythms

A-J Li, T T Dinh, Q Wang, M F Wiater, S Ritter

featuring IT-47 Leptin-SAP (Poster; Monday, Nov. 15, 2:00 pm – 3:00 pm)

733.6 Leptin-saporin lesions of the arcuate nucleus induce an arrhythmic circadian feeding pattern

M F Wiater, M Oostrom, R Barfield, T T Dinh, A-J Li, S Ritter

featuring IT-47 Leptin-SAP; IT-21 Blank-SAP (Nanosymposium; Wednesday, Nov. 17, 9:15 am – 9:30 am )

585.2/XX16 Targeting inhibitory neurons in the superficial dorsal horn: Neurotensin-saporin (NTS-sap) and neurotensin-cholera toxin A subunit (NTS-CTA)

R G Wiley, L L Lemons, K Chatterjee

featuring IT-56 Neurotensin-SAP; Custom Conjugate Neurotensin-CTA (Poster; Tuesday, Nov. 16, 9:00 am -10:00 am)