192-IgG is the antibody to the p75 neurotrophin receptor (p75NTR). The p75NTR, also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective cellular populations to programmed cell death.
This fluorescent conjugate recognizes p75 receptor-positive cells in rat. It was prepared using mouse monoclonal antibody 192-IgG conjugated to Alexa 488. This product is routinely tested by flow cytometry.
Applications include flow cytometry, fluorescence spectroscopy, fluorescence anisotropy, epifluorescence microscopy, qualitative probe of binding to membrane-bound IgG’s and the cytoskeleton.
Other NGFR Products:
NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01) | NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP) | NGFr (mu p75) Rabbit Polyclonal, affinity-purified biotin-labeled (Cat. #AB-N01APBT) | NGFr (mu p75) Rabbit Polyclonal, affinity-purified Cy3-labeled (Cat. #AB-N01APFL3) | NGFr (mu p75) Rabbit Polyclonal, affinity-purified Cy5-labeled (Cat. #AB-N01APFL5) | NGFr (mu p75) Rabbit Polyclonal, affinity-purified Alexa488-labeled (Cat. #AB-N01APFLA)