NGFR (mu p75) Rabbit Polyclonal, Cy3-labeled affinity-purified [AB-N01AP-FL3]


SKU: AB-N01AP-FL3 Categories: , Quantity: 50 ug | Antibody Type: affinity-purified, Polyclonal | Host: rabbit | Reactivity: mouse | Conjugate: Cy3 | Usage: flow cytometry |

The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor (NGFR), binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective cellular populations to programmed cell death.

This fluorescent conjugate recognizes p75NTR in mouse. It was prepared using affinity-purified rabbit polyclonal antibody conjugated to Cy3 fluorochrome. This product is routinely tested by flow cytometry.

Applications include flow cytometry.

keywords: P75NTR, NGFR, Alzheimer’s Disease, dementia, CBF neurons, cholinergic forebrain, animal model, neuronal loss, low affinity nerve growth factor, neurotrophin receptors, mesenchyme, Anti-NGFR, Anti-Nerve Growth Factor, mup75, mu p75, fluorescent, cy3, brain, neuroscience


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Adenosine inhibits glutamatergic input to basal forebrain cholinergic neurons.

Hawryluk JM, Ferrari LL, Keating SA, Arrigoni E (2012) Adenosine inhibits glutamatergic input to basal forebrain cholinergic neurons. J Neurophysiol 107(10):2769-2781. doi: 10.1152/jn.00528.2011 PMID: 22357797

Summary: Using patch-clamp recordings from mouse brain slices the authors demonstrate that adenosine not only directly inhibits cholinergic neurons in the basal forebrain, it also reduces excitatory inputs to these neurons as well. Cy3-anti-mu p75 (Cat. #FL-05, 40-60 ng) was injected into the lateral cerebroventricle.

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A highly specific NGFR antibody

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