The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor (NGFR), binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective cellular populations to programmed cell death.
This fluorescent conjugate recognizes p75NTR in mouse. It was prepared using affinity-purified rabbit polyclonal antibody conjugated to Cy5 fluorochrome. This antibody is routinely tested by flow cytometry.
Applications include flow cytometry.
keywords: P75NTR, NGFR, Alzheimer’s Disease, dementia, CBF neurons, cholinergic forebrain, animal model, neuronal loss, low affinity nerve growth factor, neurotrophin receptors, mesenchyme, Anti-NGFR, Anti-Nerve Growth Factor, mup75, mu p75, fluorescent, Cy5