The Advanced Targeting Systems targeting technology provides immunologists with the tools to identify, visualize, and or eliminate specific cell types. Some examples of scientific studies using ATS products include B-Cell targeting, T-cell targeting, depletion of inflammatory dendritic cells, increasing the success rate of transplantations, and the study of diseases of the immune system.
Use the links below to examine the ATS toolbox for solutions to your immunological challenges.
Biotin-Z Internalization Kit
Use cell surface markers to bind and internalize molecules into specific cell types. Eliminating specific cell types can reveal the function of the cell and its impact on behavior.
ZAP Antibody Internalization Kit
A description of the components in an Antibody Internalization Kit by Advanced Targeting Systems. This kit is used to screen antibodies for their specificity and ability to internalize. The technology uses a secondary antibody conjugated to saporin. Simply mix the Secondary ZAP conjugate with your primary antibody to make your own targeted toxin. Apply the targeted toxin to cells that express the receptor your antibody is targeting. Develop the cytotoxicity assay to determine whether your antibody recognizes the target receptor. This assay is used to screen multiple antibodies for the same target to determine which is the best antibody to continue development as a drug or research tool.