a tool for eliminating cells that express murine PirB (paired immunoglobulin-like receptor B) and p75 receptor expressing cells; targeted via a 42 amino acid Amyloid Beta peptide and eliminated via saporin
This kit includes 25 ug Amyloid Beta 42-SAP Kit (BETA-032), 25 ug Blank-Streptavidin-SAP (IT-27B)
Amyloid Beta 42-SAP [BETA-032] Read More »
VIP-streptavdin-saporin
This kit includes 25 ug VIP-SAP Kit (BETA-027), 25 ug Blank-Streptavidin-SAP (IT-27B)
VIP-SAP [BETA-027] Read More »
a tool for eliminating cells that express the PTH2 receptor; targeted via the TIP39 peptide, eliminated via saporin
This kit includes 25 ug TIP39-SAP Kit (BETA-030), 25 ug Blank-Streptavidin-SAP (IT-27B)
TIP39-SAP [BETA-030] Read More »
nociceptin-streptavidin-saporin
This kit includes 25 ug Nociceptin-SAP Kit (BETA-001), 25 ug Blank-Streptavidin-SAP (IT-27B)
Nociceptin-SAP [BETA-001] Read More »
alpha-CGRP-streptavidin-saporin
This kit includes 25 ug CGRP-SAP Kit (BETA-011), 25 ug Blank-Streptavidin-SAP (IT-27B)
CGRP-SAP [BETA-011] Read More »
Fulton S, Horn CC, Zhang C (2024) Characterizing a new tool to manipulate area postrema GLP1R+ neurons across species. Physiol Behav 114474. doi: 10.1016/j.physbeh.2024.114474 PMID: 38272107 Objective: Characterize the ligand exenatide conjugated to saporin as a tool to ablate GLP1 receptor-expressing cells from human, mice, and shrews, a small animal model capable of emesis (vomiting).
Characterizing a new tool to manipulate area postrema GLP1R+ neurons across species Read More »
a tool for eliminating cells that express VPAC1, VPAC2, or PAC1 receptors; targeted via biotinylated PACAP, eliminated via saporin
PACAP-SAP [IT-84, KIT-84] Read More »
Control Conjugates View a complete listing here. Controls are a vital part of the scientific procedure; without them it is difficult to isolate the specific effects from the non-specific or artifactual. These control conjugates are the same molecular weight, consist of similar, comparable materials and are synthesized with the same protocols as the targeted conjugates.
Control Conjugates Read More »
a tool for eliminating cells that express Neuropeptide natriuretic polypeptide b (Nppb or BNP) receptor; targeted via mouse BNP-32, eliminated via saporin
Nppb-SAP [IT-69, KIT-69] Read More »
a tool for eliminating cells that express specific galactose residues; targeted via MOA, eliminated via saporin
MOA-SAP [IT-92, KIT-92] Read More »