TOOLS FOR SELECTIVELY ALTERING CELLS BASED ON CELL-SURFACE MARKERS
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SERVICES FOR SELECTIVELY ALTERING AND ASSAYING CELLS
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Check out these recent publications!
IT-40: Bombesin-SAP Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors(2020) Barry DM, et al. Nat Commun 11 (1):1397.
IT-14: CTB-SAP Exercise promotes recovery after motoneuron injury via hormonal mechanisms(2020) Chew C, et al. Neural Regen Res 15 (8):1373-1376.
AB-N38: Anti-Melanopsin nGnGAmacrine Cells and Brn3b-negative M1 ipRGCs are Specifically Labeled in the ChAT-ChR2-EYFP Mouse(2020) Cui LJ, et al. Invest Ophthalmol Vis Sci 61 (2):14.
IT-20: Orexin-SAP A common neuronal mechanism of hypertension and sleep disturbances in spontaneously hypertensive rats: Role of orexinergic neurons(2020) Cui S-Y, et al. Progress in Neuro-Psychopharmacology and Biological Psychiatry 100: 109902.
IT-11: SSP-SAP A role for neurokinin 1 receptor expressing neurons in the paratrigeminal nucleus in bradykinin-evoked cough in guinea pigs(2020) Driessen AK, et al. J Physiol 598(11):2257-2275
IT-47: Leptin-SAP Loss of leptin-receptor expressing cells in the hindbrain decreases forebrain leptin sensitivity (2020) Harris RBS. Am J Physiol Endocrinol Metab 318(5):E806-E816
Custom Conjugation Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls (2020) Knuplez E, et al. J Leukoc Biol 108:43-58
IT-40: Bombesin-SAP More than Scratching the Surface: Recent Progress in Brain Mechanisms Underlying Itch and Scratch (2020) Liu X, et al. Neurosci Bull 36 (1):85-88.
IT-03: Anti-DBH-SAP An age- and sex-dependent role of catecholaminergic neurons in the control of breathing and hypoxic chemoreflex during postnatal development (2020) Patrone LGA, et al. Brain Res 1726: 146508.
IT-10: IB4-SAP Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice (2019) Pinto LG, et al. Mol Neurobiol 56(8):5715-5728
Urotensin II-SAP IT-21: Blank-SAP Cholinergic basal forebrain degeneration due to obstructive sleep apnoea increases Alzheimer’s pathology in mice(2020) Qian L, et al. bioRxiv 2020.03.12.989848.
IT-27: Streptavidin-ZAP ALPPL2 is a highly specific and targetable tumor cell surface antigen (2020) Su Y, et al. bioRxiv 2020.01.07.898122.
IT-01: 192-IgG-SAP IntracerebroventricularAdministration of 192IgG-Saporin Alters the State of Microglia in the Neocortex (2020) Volobueva MN, et al. Neurochem J 14: (1):37-42.
Assay and Conjugation Services
Custom Conjugates are powerful tools that deliver specific payloads to targeted cell types. This technique has important applications in determining the function or contribution of the targeted cells in a biological system or for the removal of interfering cell types.
Cell and Plate-Based Assays
Screening large numbers of peptides or proteins such as antibodies can be prohibitively expensive in both cost and time. From antibody and compound internalization assays to ELISAs and Fluorescent Microscopy, there are a wide array of kits and services for all of your cell and plate-based assays.
for specificity and/or internalization.
Four levels of service available:
- 1-5 cell lines
1 compound: 6 doses / 1 time-point, 2 controls – or – 2 to 6 compounds: 1 dose / 1 time-point, 2 controls
- 15 cell lines
- 30 cell lines
- 60 cell lines or more!
Transfections can be a time-consuming and tedious process. Let CytoLogistics help you with the experimental design and laboratory assays to create and assay the transfected cells. CytoLogistics provides transfection services utilizing our new Transfection Perfection™ selection method ensuring a population of high-expressing cells. This method of selection provides a means of purifying the highest expressing transfected populations using a more cost-effective and time-saving approach.