Contributed by Ekaterina Likhtik Columbia University,New York Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032 Introduction by Douglas Lappi, Ph.D., President/CSO: This quarter’s Cover Article is from Ekaterina Likhtik who reprises her recently published work in Nature 454:642-645. In the News and Views, Sah and Westbrook comment that “Neuronal receptors in these circuits—such as […]

Contributed by Jason J. Radley, Ph.D., Laboratory of Neuronal Structure and FunctionThe Salk Institute for Biological Studies and Foundation for Medical Research, La Jolla, CA 92037, USA The medial prefrontal cortex (mPFC) has been proposed to play a role in the inhibition of hypothalamo-pituitary-adrenal (HPA) responses to emotional stress via influences on neuroendocrine effector mechanisms

Contributed by Pierre-Henri Moreau, Brigitte Cosquer, Hélène Jeltsch, Jean-Christophe Cassel, Chantal MathisLaboratoire d’Imagerie et de Neurosciences Cognitives, UMR7191 CNRS,Equipe de Neurobiologie Cognitive et Comportementale, Université Louis Pasteur,IFR 37 de Neurosciences, GDR 2905 CNRS, 12 rue Goethe, 67000 Strasbourg, France The basal forebrain cholinergic neurons (BFCNs) are dramatically affected in several neurodegenerative diseases such as Alzheimer’s

Contributed by Kevin C.H. Pang, Xilu Jiao and Richard J. ServatiusNeuroscience Dept, New Jersey Med Sch – UMDNJ and VA Med Ctr – East Orange, NJ The medial septum and diagonal band of Broca (MSDB) provide a major afferent pathway to the hippocampus.[1] Cholinergic and GABAergic neurons are the main components of this pathway, but