Streptavidin-ZAP Kit Promotion

Purchase any size: Streptavidin-ZAP Internalization Kit (Cat. #KIT-27-Z) Streptavidin-ZAP Antibody Kit (Cat. #KIT-27A) Streptavidin-ZAP Peptide Kit (Cat. #KIT-27B)   and get a second one free on any online order.   Enter Code StrepBLAST. *Not good with any other promotion.       Offer expires 1 November 2018.  

Screening antibodies for cancer therapeutics

Conservation of Oncofetal Antigens on Human Embryonic Stem Cells Enables Discovery of Monoclonal Antibodies against Cancer. Tan HL, Yong C, Tan BZ, Fong WJ, Padmanabhan J, Chin A, Ding V, Lau A, Zheng L, Bi X, Yang Y, & Choo A. (2018). Scientific Reports, 8 (1):11608. This study used both Hum-ZAP (Cat. #IT-22) and Streptavidin-ZAP (Cat. #IT-27) […]

Cytoplasmic Delivery of Aptamers

Screening Aptamers as Targeting Agents to deliver Payloads. Aptamers are small, synthetic, single-stranded nucleic acids that fold into unique secondary structures. Unlike peptides and monoclonal antibodies, they are essentially non-immunogenic even when administered in excess amounts. The publications below explain how biotinylated aptamers combined with Streptavidin-conjugated saporin (Streptavidin-ZAP) can be used to screen aptamers for […]

Community involvement – Feeding the Hungry

‏ Friday afternoon, Advanced Targeting Systems employees and friends volunteered at Feeding San Diego and helped reclaim over 1200 pounds of food to feed the hungry.  It was a great time of teamwork and giving back to the community. @AdvTargeting

Dedicated Scientific Staff

The ATS scientific staff is dedicated to providing quality targeting tools and prompt, courteous support for all of our research products. L to R: Leonardo, Raschel, Sydney, Patrick, Miguel.

Antibody Samples – Tools to study Programmed Cell Death

Antibodies you can rely on. The authors investigated the interactions of pro-survival and pro-apoptotic receptors in Programmed Cell Death (PCD) using the sympathetic nervous system as a model. They demonstrate that Ret, a receptor tyrosine kinase required for the survival of many neuronal populations, is restricted to a subset of degenerating neurons that rapidly undergo […]

Striatum, dopamine neurotransmission, Dermorphin, Huntington Disease

Selective ablation of striatal striosomes produces the deregulation of dopamine nigrostriatal pathway. Objective:  To increase knowledge in the role of the striosomal projection onto the dopamine neurons of the SNc and its impact on the nigrostriatal dopamine pathway. Summary:  Results highlight the key function of the striosomes for maintenance of the striatal dopamine tone and […]

Breathing, Parkinson’s Disease and Targeting Orexin Receptors

Orexin-B-SAP (Cat. #IT-20): a tool for eliminating cells that express the orexin-2 receptor; targeted via orexin-B peptide, eliminated via saporin. Orexinergic Neurons Are Involved in the Chemosensory Control of Breathing During the Dark Phase in a Parkinson’s Disease Model. Oliveira LM, Falquetto B, Moreira TS, & Takakura AC (2018) Exper Neurol, 309:107-118. Objective:  To determine […]

Antibodies You Can Rely On!

For a limited time only: 2 special promotions – Get a free sample of any of the listed antibodies • OR • Buy any antibody on the list and get a second antibody for FREE! Just enter coupon code AntibodyBogo at checkout. Your discount will be applied and confirmed via email. Choose from the following products: 192 […]