Immunology 2022

Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 339 May 7-9 and find out how you can use Molecular Surgery to accelerate your Immunology research!

Targeting Trends 2021 Review

Read the complete 2021 Review. Targeted Ablation with IB4-SAP: Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis Scientific References Top 20 Targeting Tools

Top 20 Targeting Tools of 2021

Top Five Targeted Toxins #1. CTB-SAP  (Cat. #IT-14) – targets cells expressing GM1 receptor #2 Mac-1-SAP (Cat. #IT-06) – targets cells expressing Mac-1 (CD11b ) receptor #3 Anti-CD103-SAP (Cat. #IT-50) – targets cells expressing CD103 #4. Anti-DBH-SAP (Cat. #IT-03) – targets cells expressing rat dopamine beta-hydroxylase  #5. mu p75-SAP (Cat. #IT-16) – targets cells expressing mouse …

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Targeted Ablation with IB4-SAP

Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis Kayla L. Nguyen1, Sydney R. Lamerand1, Ronit P. Deshpande1, Bradley K. Taylor1,2 1Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA2Center for Neuroscience at the University of Pittsburgh, Pittsburgh, PA …

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Top 20 Targeting Tools of 2020

Top Five Targeted Toxins #1. CTB-SAP  (Cat. #IT-14) – targets cells expressing GM1 receptor #2. Anti-DBH-SAP (Cat. #IT-03) – targets cells expressing rat dopamine beta-hydroxylase  #3. IB4-SAP (Cat. #IT-10) – targets cells expressing alpha-D-galactopyranoside residues #4. mu p75-SAP (Cat. #IT-16) – targets cells expressing mouse p75NTR #5. ME20.4-SAP (Cat. #IT-15) – targets cells expressing multiple mammalian …

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Targeting Trends 2020 Review

Read the complete 2020 Review. Navigating the Turbulent Waters of the Pandemic Scientific References Top 20 Targeting Tools

American Association for Cancer Research, AACR 2022

Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 1319 April 9-13 and find out how you can use Molecular Surgery to discover a cure for cancer.

Abstracts from Society for Neuroscience (SFN) November 8-11, 2021 – Virtual Meeting

P210 / 07 Effects of age on sexually dimorphic food protection behavior associated with hippocampal cholinergic deafferentation. J. R. OSTERLUND OLTMANNS1, E. A. SCHAEFFER1, A. A. BLACKWELL1, S. A. PIETRUCHA1, H. YANG1, S. TSAI2, G. L. KARTJE2, *D. WALLACE1 featuring IT-01 192-IgG-SAP Loss of hippocampal cholinergic projection originating from basal forebrain structures has been associated …

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