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Tools and Services to Advance your Research and Drug Development
TOOLS FOR SELECTIVELY ALTERING CELLS BASED ON CELL-SURFACE MARKERS You’re still publishing and we’re still open to meet your targeting needs. You can place your orders online or contact us. Stay safe and healthy!Denise Higginswww.ATSbio.com SERVICES FOR SELECTIVELY ALTERING AND ASSAYING CELLS Restricted access can slow or halt your research and drug development activities. We …
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New Location
c/o CytoLogistics, LLC6352-B Corte del AbetoCarlsbad, CA 92011
Cover Article: Targeted Toxins – Cheaper and Quicker than Knockouts
Cell-specific targeting and removal: cheaper and quicker than knockouts with high impact results. Knockout models are helpful tools in scientific research. They have been useful in studying and modeling in all sorts of research in biology; so much so that the pioneers – Smithies, Capecchi and Evans – won a well-deserved Nobel Prize for Physiology …
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Recent Publications using ATS Products
Borkowski LF, & Nichols NL. A2A and 5-HT Receptors are Differentially Required for Respiratory Plasticity Over the Course of Motor Neuron Loss in Intrapleurally CTB-SAP Treated Rats. (2019). FASEB J, 33 (1_supplement):843.843-843.843. IT-14: CTB-SAP Dose: Bilateral, intrapleural injections of: 1) CTB-SAP (25 μg), or 2) un-conjugated CTB and SAP (control) in rats. Toledo C, Andrade …
Research Tools for Parkinson’s Disease
A review of the tools for studying Parkinson’s Disease These results show that an antibody to the extracellular domain of the dopamine transporter (DAT) can be used to target midbrain dopaminergic neurons and that Anti-DAT-Saporin may be useful for producing a lesion very similar to the naturally-occurring neural degeneration seen in Parkinson’s Disease (Wiley et …
Alzheimer’s Disease models
A review of the tools for creating animal models of Alzheimer’s Disease “192 IgG-saporin binds selectively and irreversibly to low-affinity nerve growth factor receptor interrupting cholinergic neuronal protein synthesis.” “Anti-DBH-SAP allows a selective and gradual lesioning of noradrenergic neurones in the brain stem nucleus locus coeruleus, the primary site of noradrenaline production in the CNS.” …
Award winner for animal model of temporal lobe epilepsy
Congratulations to Dr. Argyle Bumanglag and the team at University of Florida for the important work they presented using SSP-SAP to create an animal model of temporal lobe epilepsy. Injections of SSP-SAP into the hippocampus of a rat causes acute hippocampal injury, permanent dentate granule cell-onset epilepsy, and hippocampal sclerosis that closely resembles the selective …
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Abstracts from Society for Neuroscience (SFN) Symposium October 19-23, 2019 – Chicago, IL
048.01 / F11 – Increased transplantation efficacy of mesenchymal stem cell by focused ultrasound and improvement of the spatial memory in the 192 IgG-saporin rat model *J. LEE1,2, Y. SEO1,2, J. SHIN1,2, C. KONG1, Y. NA3, W. CHANG1, J. CHANG1,2; featuring IT-01 192-IgG-SAP 052.10 / H30 – Nociceptors expressing TRPV1 and trigeminal nucleus neurons expressing …
New product announcements at SfN: Transfection and Epilepsy tools
Come visit us at The Society for Neuroscience in Chicago – October 19-23, Booth #763. We have some exciting new products to talk to you about. Cell Transfection Kit & Service Temporal Lobe Epilepsy Animal Model