F055 Behavioral effects of immunotoxin 192IgG-saporin depends on the type of its administration to rats. Yulia Dobryakova, Alexey Bolshakov, Maria Zaichenko, Mikhail Stepanichev, Vlaimir Markevich featuring IT-01 192-IgG-SAP (Sunday 2:00pm-5:30pm) It is known that degeneration of cholinergic neurons is one of key events during development of Alzheimer’s disease. We used immunotoxin 192IgG-saporin, a conjugate of antibody to […]

72.2 /KK24 Glutamate and adenosine, basal forebrain andcortex: Cross-talk during prolonged wakefulness A A Larin, S A Karpova, R W Mccarley, R Basheer, A V Kalinchuk featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov. 11, 1:00 PM – 5:00 PM) Recently we described a biochemical cascade which is critical in promoting recovery sleep (RS) after sleep deprivation […]

38.10 / G29 Placenta-derived mesenchymal stem cells facilitate neural and cognitive recovery in dementia rat model. J Cho, J Lee,, D Jeong, H Kim, W Chang, J Moon,, J Chang, featuring IT-01 192-IgG-SAP (Poster; Saturday, Nov. 12, 1:00 PM – 5:00 PM) 77.09 / AAA24 Diacylglycerol lipase-α expression increases in the coeruleo-cortical pathway in dopamine-β-hydroxylase […]

40.29/C34 Preliminary investigation on the antidepressive effect of chronic oxotremorine treatment in a rodent model of Alzheimer’s disease D V Nair, M M Al-Badri, H Peng, J Pacheco-Quinto, C B Eckman, D Iacono, E A Eckman featuring IT-01 192-IgG-SAP (Poster; Saturday, Oct. 17, 1:00 PM – 5:00 PM) 6.07 Modeling Tourette syndrome pathophysiology through targeted […]

692.21 Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PD K Phillips, A Kucinski, R Albin, M Sarter featuring IT-42 Anti-ChAT-SAP (poster; Wednesday, Nov. 19, 8:00 AM – 12:00 PM) In addition to striatal dopamine loss, degeneration of cholinergic neurons in the basal forebrain (BF) and the […]

134.02 Memory and cholinergic impairment using a new approach of bilateral lesion of rat cholinergic basal forebrain I Manuel, A Llorente, E González De San Román, L Merino, M Giralt, R Rodriguez-Puertas featuring IT-01 192-IgG-SAP (poster; Sunday, Nov. 16, 8:00 AM – 12:00 PM) 158.02 Spinal antinociceptive effect of gastrin releasing peptide (GRP) via GABAergic […]

266.15 Role of nonpeptidergic subset of primary afferent neurons in inflammatory hypernociception in mice. L G Pinto, G R Souza, A H P Lopes, J Talbot, F Q Cunha, T M Cunha, S H Ferreira featuring IT-10 IB4-SAP (Poster; Sunday, November 10, 3:00 pm – 4:00 pm) 274.01 Ablation of arcuate KNDy neurons amplifies the […]

Awarded by ATS at Society for Neuroscience (SFN) November 9-13, 2013 • San Diego, CA 699.04 CD4+ T lymphocytes interact with microglia to modulate hippocampal neurogenesis. D Khan, E Owens, M Zaben, S B Dunnett, W P Gray, featuring IT-33 Mac-1-SAP rat (Poster; Wednesday, November 13, 11:00 am – 12:00 pm) Hippocampal neurogenesis occurs within […]

164.19 Knockdown of noradrenergic locus coeruleus (LC) neurons alleviates chronic orofacial pain R Kaushal, F Ma, L Zhang, C R Bright, B K Taylor, K N Westlund featuring IT-03 Anti-DBH-SAP (Poster; Sunday, Oct. 14, 10:00 am – 11:00 am) 203.28 Combined loss of entorhinal and basal forebrain cholinergic hippocampal inputs deeply impairs spatial navigation memory […]

Awarded by ATS at Society for Neuroscience (SFN) October 13-17, 2012 • New Orleans, LA 496.03 The GRP peptide and the GRPR-positive interneurons control fear acquisition and extinction. K Zushida, K Light, S Uchida, C Hevi, G P Shumyatsky featuring IT-40 Bombesin-SAP (Poster; Monday, Oct. 15, 3:00 pm – 4:00 pm) The gastrin releasing peptide […]