Proteins come in all shapes and sizes and don’t always contain a ready-to-conjugate binding site. ATS scientists are conjugation experts when it comes to crosslinking peptides, antibodies, and other proteins. Whether you are in need of a Saporin conjugate, biotin labeling, fluorochrome labeling, ADC’s, or other toxin conjugates, we can help you design a strategy […]
Targeting Tools: Custom Conjugates – Made to Order Read More »
by Kristen Ashley Horner and collaborators R. Murray and M.C. LoganMercer University School of Medicine, Savannah, GA 31404 Repeated exposure to psychostimulants, such as cocaine, can result in patterns of repetitive, inflexible behaviors, known as stereotypy.[1,2] These inflexible behaviors are thought to be similar to the type of behaviors observed with certain psychiatric disorders, such
Read the 2015 Newsletters and recent scientific references 2015, issue 1: Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in Parkinson’s Disease / by Aaron Kucinski / featuring 192-IgG-SAP (Cat. #IT-01), Anti-ChAT-SAP (Cat. #IT-42) Society for Neuroscience Poster of the Year Award Veterinary Development of Substance P-Saporin (SP-SAP) Targeting Talk:
Targeting Trends 2015 Newsletter Read More »
Humana Press has released its newest offer to the Neuroscience community, Molecular Neurosurgery With Targeted Toxins, with Ronald G. Wiley and Douglas A. Lappi as editors. This book contains articles by “the best and the brightest” who have used targeted toxins for probing difficult in vivo systems biology issues. To order — please contact ATS
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Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish keywords: biotinylated molecules, screen, Biotin-Z Internalization kit, binding, internalization, targeting agent, cell surface marker, saporin, custom, streptavidin, Streptavidin-ZAP, secondary
Biotin-Z Internalization Kit Tutorial Read More »
Also available in Japanese | German | French | Korean | Mandarin | Italian | Spanish A description of the components in an Antibody Internalization Kit by Advanced Targeting Systems. This kit is used to screen antibodies for their specificity and ability to internalize. The technology uses a secondary antibody conjugated to saporin. Simply mix
ZAP Antibody Internalization Kit Tutorial Read More »
Congratulations to this year’s winner of ATS’ Poster of the Year featuring Dermorphin-SAP (Cat. #IT-12). Horner KA, Logan M, Murray RC (2015) Ablation of the patch compartment reduces cocaine-induced stereotypy. Neuroscience 2015 Abstracts 506.23/M12. Society for Neuroscience, Chicago IL Be sure to check out the featured article in Targeting Trends. Repeated exposure to cocaine (COC) induces
SFN Poster of the Year 2015 Read More »
Internalization Technology to eliminate specific cells Advanced Targeting Systems’ technology – Molecular Surgery – is a modification of one of the most widely used techniques in the neurosciences: lesioning of a region by surgical means and observation of the effect. Saporin has no way of entering a cell on its own, except by bulk-phase endocytosis.
Technology Tutorial Read More »