Abstracts from Society for Neuroscience (SFN) Chicago, IL • October 17-21, 2009
Abstracts from Society for Neuroscience (SFN) Chicago, IL • October 17-21, 2009 Read More »
SFN Poster of the Year 2009
Awarded by ATS at Society for Neuroscience (SFN) Chicago, IL • October 17-21, 2009 Be sure to check out the featured article in Targeting Trends. 374.5/EE116 Leptin-saporin injection into the arcuate nucleus lesions NPY/AGRP and POMC neurons and produces hyperphagia, obesity and changes in diurnal feeding patterns in ratsA-J Li, Q Wang, T T Dinh, S
SFN Poster of the Year 2009 Read More »
The role of microglia and neuropeptides in regulating hippocampal neurogenesis.
Sivasathiaseelan H, Nunan R, Zaben M, Shtaya A, Gray WP (2009) The role of microglia and neuropeptides in regulating hippocampal neurogenesis. Neuroscience 2009 Abstracts 31.26/B52. Society for Neuroscience, Chicago, IL. Summary: Adult mammalian neurogenesis is evident in the hippocampal dentate gyrus where it plays a role in learning and memory and is implicated in the
The role of microglia and neuropeptides in regulating hippocampal neurogenesis. Read More »
Caudal hindbrain catecholaminergic projection to the ventrolateral bed nucleus of the stria terminalis (vlBNST): Assessment of role in glucoprivic and CCK feeding responses and corticosterone secretion.
Dinh TT, Huston NJ, Ritter S (2009) Caudal hindbrain catecholaminergic projection to the ventrolateral bed nucleus of the stria terminalis (vlBNST): Assessment of role in glucoprivic and CCK feeding responses and corticosterone secretion. Neuroscience 2009 Abstracts 87.16/CC80. Society for Neuroscience, Chicago, IL. Summary: Catecholamine neurons in the caudal hindbrain provide a significant innervation of the
Role of cholinergic NBM neurons in timing and divided attention.
Mcauley J, Stewart AL, Pang KCH (2009) Role of cholinergic NBM neurons in timing and divided attention. Neuroscience 2009 Abstracts 95.12/EE81. Society for Neuroscience, Chicago, IL. Summary: The nucleus basalis magnocellularis (NBM) provides cholinergic and GABAergic innervation to the neocortex. In previous studies, non-selective lesions of the NBM using ibotenic acid impaired interval timing and
Role of cholinergic NBM neurons in timing and divided attention. Read More »
Multiple neuromodulator depletion interacts with fornix transection to impair episodic memory in monkeys.
Croxson PL, Baxter MG (2009) Multiple neuromodulator depletion interacts with fornix transection to impair episodic memory in monkeys. Neuroscience 2009 Abstracts 98.4/EE128. Society for Neuroscience, Chicago, IL. Summary: Acetylcholine may play an important role in some aspects of cognitive function, and in particular in episodic memory. However, the role of other neuromodulatory (NM) substances, such
Targeting Tools: Oxytocin-SAP
Oxytocin-SAP (Cat. #IT-46) is a conjugate (molecular weight 31 kDa) between the native oxytocin peptide and saporin. Oxytocin is a nine amino acid peptide with a structure similar to vasopressin, and is a hormone released by the posterior pituitary. Peripheral activity of oxytocin is linked primarily to lactation and labor-related uterine contractions. Within the brain,
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Targeting Tools: Anti-Basigin
This mouse monoclonal antibody (Cat. #AB-42; Clone P2C2) recognizes human Basigin. The antibody is purified by ammonium sulfate precipitation on conditioned medium and then further purified through Protein-A. The antibody is routinely tested by flow cytometry. The immunoglobulin superfamily protein basigin (EMMPRIN/CD147) is a cell surface glycoprotein expressed by tumor cells that stimulates matrix metalloproteinase
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Targeting Tools: Bombesin-SAP
Bombesin-SAP (Cat. #IT-40) specifically targets and eliminates gastrin- releasing peptide receptor (GRPR)-positive cells. This targeted toxin (molecular weight 31.8 kDa) is a chemical conjugate of bombesin and the ribosome-inactivating protein, saporin. Please see cover article (pp. 1, 6) for an example of its experimental use.
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Nitrous oxide-induced analgesia does not influence nitrous oxide’s immobilizing requirements.
Jinks SL, Carstens E, Antognini JF (2009) Nitrous oxide-induced analgesia does not influence nitrous oxide’s immobilizing requirements. Anesth Analg 109:1111-1116. doi: 10.1213/ANE.0b013e3181b5a2a7 Summary: Noradrenergic neurons in the locus coeruleus (LC) are involved with the analgesic action of nitrous oxide (N2O). In order to examine whether these neurons are also involved with the immobilizing effects of