Targeting Tools: Bombesin-SAP

Bombesin-SAP (Cat. #IT-40) specifically targets and eliminates gastrin- releasing peptide receptor (GRPR)-positive cells. This targeted toxin (molecular weight 31.8 kDa) is a chemical conjugate of bombesin and the ribosome-inactivating protein, saporin. Please see cover article (pp. 1, 6) for an example of its experimental use.