Bombesin-SAP [IT-40]

a tool for eliminating cells that express gastrin releasing peptide (GRP) receptor; targeted via bombesin, eliminated via saporin

 

Clear
SKU: IT-40 Category: Product Size: 25 ug, 100 ug, 250 ug, 1 mg |

Description

Bombesin is a 14-amino-acid peptide found in frog-skin. The human equivalent, gastrin releasing peptide (GRP) has been detected in itch pathways and plays a role in eating behaviors. GRP regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.
IT-40

Bombesin-SAP (GRPR-SAP) specifically targets GRP receptor-positive cells. All other cells are left untouched. Elimination of cells expressing GPR receptor is useful in studying the role of bombesin in itch and eating behaviors.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

View Data Sheet

View Related References

You may also like…