Rock JR, Onaitis MW, Rawlins EL, Lu Y, Clark CP, Xue Y, Randell SH, Hogan BL (2009) Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A 106(31):12771-12775. doi: 10.1073/pnas.0906850106 PMID: 19625615 Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)
Basal cells as stem cells of the mouse trachea and human airway epithelium Read More »
Zhang L, Moffatt-Bruce SD, Gaughan AA, Wang JJ, Rajab A, Hadley GA (2009) An anti-CD103 immunotoxin promotes long-term survival of pancreatic islet allografts. Am J Transplant 9:2012-2023. doi: 10.1111/j.1600-6143.2009.02735.x PMID: 19645708 Objective: To determine whether blockade of the CD103 pathway represents a viable therapeutic strategy for intervention in organ allograft rejection and graft-vs-host disease. Summary:
An anti-CD103 immunotoxin promotes long-term survival of pancreatic islet allografts. Read More »
Vetrivelan R, Fuller PM, Tong Q, Lu J (2009) Medullary circuitry regulating rapid eye movement sleep and motor atonia. J Neurosci 29:9361-9369. doi: 10.1523/JNEUROSCI.0737-09.2009 Summary: Data concerning rapid-eye movement (REM) motor atonia in rats has not agreed with results seen in large amount of data from cats. Here the authors traced the medullary networks in
Medullary circuitry regulating rapid eye movement sleep and motor atonia. Read More »
Kaur S, Thankachan S, Begum S, Liu M, Blanco-Centurion C, Shiromani PJ (2009) Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice. PLoS One 4:e6346. doi: 10.1371/journal.pone.0006346 Summary: Not all connections between narcolepsy and orexin are understood, since orexin neurons are located in the lateral hypothalamus and some
Montero M, Gonzalez B, Zimmer J (2009) Featured Article: Depletion of microglia by Mac-1-SAP in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Targeting Trends 10(3) Related Products: Mac-1-SAP mouse/human (Cat. #IT-06) Read the featured article in Targeting Trends. See Also: Montero M et al. Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like
Lopez-Aranda MF, Lopez-Tellez JF, Navarro-Lobato I, Masmudi-Martin M, Gutierrez A, Khan ZU (2009) Role of layer 6 of V2 visual cortex in object-recognition memory. Science 325:87-89. doi: 10.1126/science.1170869 Summary: The authors examined the role of the V2 visual cortex in visual memory. Working with the prediction that object-recognition memory (ORM) control is centered in the
Role of layer 6 of V2 visual cortex in object-recognition memory. Read More »
ATS has been awarded a Phase I SBIR grant to develop a new line of products. Dr. Douglas Lappi is the Principal Investigator and Brian Russell is the Lead Scientist on the project. Molecules targeted towards cell surface markers have been used for years to identify specific cell types. It has been demonstrated over the
Targeting Article: SBIR Grant Funded: Selective Activation in Neuronal Populations Read More »
Contributed by Maria Montero (a), Berta Gonzalez (b), Jens Zimmer (a)(a) Anatomy and Neurobiology, University of Southern Denmark, Denmark(b) Histology Unit, Autonomous University of Barcelona, Spain Microglial cells contribute about 12% of the cells in the brain, acting as “biosensors” for homeostatic regulation in normal and pathological conditions.[3,13] Resting microglial cells in the adult brain
Esclassan F, Coutureau E, Di Scala G, Marchand AR (2009) A cholinergic-dependent role for the entorhinal cortex in trace fear conditioning. J Neurosci 29:8087-8093. doi: 10.1523/JNEUROSCI.0543-09.2009 Summary: Higher cognitive involvement can be modeled through the use of trace conditioning in simple associative tasks. Rats received several 20-80 ng injections of 192-IgG-SAP (Cat. #IT-01) into the
A cholinergic-dependent role for the entorhinal cortex in trace fear conditioning. Read More »
Cao F, Chen SS, Yan XF, Xiao XP, Liu XJ, Yang SB, Xu AJ, Gao F, Yang H, Chen ZJ, Tian YK (2009) Evaluation of side effects through selective ablation of the mu opioid receptor expressing descending nociceptive facilitatory neurons in the rostral ventromedial medulla with dermorphin-saporin. Neurotoxicology 30(6):1096-1106. doi: 10.1016/j.neuro.2009.06.004 Summary: Selective ablation of