Di Sebastiano AR, Yong-Yow S, Wagner L, Lehman MN, Coolen LM (2010) Orexin mediates initiation of sexual behavior in sexually naive male rats, but is not critical for sexual performance. Horm Behav 58(3):397-404. doi: 10.1016/j.yhbeh.2010.06.004 Summary: In this work the role of endogenous orexin-A and B in male sexual behavior was investigated. Rats received a […]
Adachi T, Huxtable AG, Fang X, Funk GD (2010) Substance P modulation of hypoglossal motoneuron excitability during development: changing balance between conductances. J Neurophysiol 104(2):854-872. doi: 10.1152/jn.00016.2010 PMID: 20538779 Summary: This work examined how neuromuscular networks that are immature, but functional, at birth move through development while remaining operational. The authors focused on hypoglossal motoneurons
Luo T, Leung LS (2010) Endogenous histamine facilitates long-term potentiation in the hippocampus during walking. J Neurosci 30(23):7845-7852. doi: 10.1523/JNEUROSCI.1127-10.2010 Summary: The neurotransmitter histamine is involved in several physiological functions, such as sleep-wake activites, circadian rhythms, learning, and memory. This work examines the role of histamine in modulating synaptic plasticity. Rats received 62.5 ng injections
Gil-Bea FJ, Solas M, Mateos L, Winblad B, Ramirez MJ, Cedazo-Minguez A (2011) Cholinergic hypofunction impairs memory acquisition possibly through hippocampal Arc and BDNF downregulation. Hippocampus 21(9):999-1009. doi: 10.1002/hipo.20812 Summary: The authors investigated the role of activity-regulated cytoskeleton associated protein (Arc) and brain-derived neurotrophic factor (BDNF) in cholinergic-induced memory formation. Rats received 67-ng bilateral injections
Worlicek M, Knebel K, Linde HJ, Moleda L, Scholmerich J, Straub RH, Wiest R (2010) Splanchnic sympathectomy prevents translocation and spreading of E coli but not S aureus in liver cirrhosis. Gut 59(8):1127-1134. doi: 10.1136/gut.2009.185413 Summary: Advanced cirrhosis activates the sympathetic nervous system. This work investigates the role of the sympathetic nervous system (SNS) in
Easton A, Fitchett AE, Eacott MJ, Baxter MG (2011) Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory. Hippocampus 21(9):1021-1027. doi: 10.1002/hipo.20814 Summary: Although it is clear that neurodegenerative diseases cause memory impairment, it is uncertain to what extent cholinergic deficits cause this loss of function. The authors administered a total
Paban V, Farioli F, Romier B, Chambon C, Alescio-Lautier B (2010) Gene expression profile in rat hippocampus with and without memory deficit. Neurobiol Learn Mem 94(1):42-56. doi: 10.1016/j.nlm.2010.03.005 Summary: This work examined a wide range of gene expression in the rat hippocampus after bilateral injections of 192-IgG-SAP (Cat. #IT-01) – 37.5 ng per side in
Gene expression profile in rat hippocampus with and without memory deficit. Read More »
Pang KCH, Jiao X, Sinha S, Beck KD, Servatius RJ (2011) Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: Effects on proactive interference. Hippocampus 21(8):835-846. doi: 10.1002/hipo.20799 Summary: Recent work implicates the medial septum (MS) and diagonal band (DB) in the control of proactive interference —
Lyu MA, Rai D, Ahn KS, Sung B, Cheung LH, Marks JW, Aggarwal BB, Aguiar RC, Gandhi V, Rosenblum MG (2010) The rGel/BLyS fusion toxin inhibits diffuse large B-cell lymphoma growth in vitro and in vivo. Neoplasia 12(5):366-375. doi: 10.1593/neo.91960
Hummel M, Cummons T, Lu P, Mark L, Harrison JE, Kennedy JD, Whiteside GT (2010) Pain is a salient “stressor” that is mediated by corticotropin-releasing factor-1 receptors. Neuropharmacology 59(3):160-166. doi: 10.1016/j.neuropharm.2010.05.001 Summary: Given that corticotrophin-releasing factor (CRF) plays a major role in the response to stress, the authors investigated the role CRF-1 receptors may play