Author name: Kristen Hartman

Featured Article: Internalization of basigin-2, a poor prognosis marker, by a monoclonal antibody

Lappi DA, Ancheta LR, Nowak RA (2010) Featured Article: Internalization of basigin-2, a poor prognosis marker, by a monoclonal antibody. Targeting Trends 11(3) PMID: 0 Related Products: Antibody to Basigin (Cat. #AB-42), Anti-Basigin2-SAP (Cat. #IT-54) Read the featured article in Targeting Trends.

Featured Article: Internalization of basigin-2, a poor prognosis marker, by a monoclonal antibody Read More »

Featured Article: Role of cell fate determinants in a model of spinal cord neurotoxic lesion induced by cholera toxin b-saporin

Gulino R, Perciavalle V, Gulisan M (2010) Featured Article: Role of cell fate determinants in a model of spinal cord neurotoxic lesion induced by cholera toxin b-saporin. Targeting Trends 11(3) Related Products: CTB-SAP (Cat. #IT-14) Read the featured article in Targeting Trends. See Also: Gulino R et al. Expression of cell fate determinants and plastic

Featured Article: Role of cell fate determinants in a model of spinal cord neurotoxic lesion induced by cholera toxin b-saporin Read More »

Contribution of limbic norepinephrine to cannabinoid-induced aversion.

Carvalho AF, Reyes AR, Sterling RC, Unterwald E, Van Bockstaele EJ (2010) Contribution of limbic norepinephrine to cannabinoid-induced aversion. Psychopharmacology (Berl) 211(4):479-491. doi: 10.1007/s00213-010-1923-7 Summary: The authors used bilateral injections of anti-DBH-SAP (Cat. #IT-03) into the nucleus accumbens and the bed nucleus of the stria terminalis to investigate the role of neuroepinephrine in cannabinoid-induced aversion

Contribution of limbic norepinephrine to cannabinoid-induced aversion. Read More »

Targeting Article: Poster at American Association for Cancer Research Meeting

At this year’s AACR meeting, Leonardo Ancheta, scientist and Product Manager from ATS, presented a poster on our new monoclonal antibody to Basigin-2 (Cat. #AB-42). The poster describes our work with the antibody and the immunotoxin made from it (Cat. #IT-54). Basigin-2 (EMMPRIN, CD147) is widely expressed on the surface of numerous tumor types and

Targeting Article: Poster at American Association for Cancer Research Meeting Read More »

Cover Article: Role of Cell Fate Determinants in a Model of Spinal Cord Neurotoxic Lesion Induced by Cholera Toxin B-Saporin

Contributed by Rosario Gulino, Vincenzo Perciavalle and Massimo Gulisan Dept of Physiological Sciences, Univ of Catania, Viale Andrea Doria, 6-I95125 Catania ITALY A promising approach for central nervous system (CNS) repair consists in the activation of endogenous neural precursor cells (NPCs), but this process is less efficient in the spinal cord (SC) following a spinal

Cover Article: Role of Cell Fate Determinants in a Model of Spinal Cord Neurotoxic Lesion Induced by Cholera Toxin B-Saporin Read More »

Morphology and mosaics of melanopsin-expressing retinal ganglion cell types in mice

Berson DM, Castrucci AM, Provencio I (2010) Morphology and mosaics of melanopsin-expressing retinal ganglion cell types in mice. J Comp Neurol 518(13):2405-2422. doi: 10.1002/cne.22381 PMID: 20503419 Objective: To provide a fuller description of murine cell types expressing melanopsin, their contribution to the plexuses of melanopsin dendrites, and mosaics formed by each type. Summary: M1 cells,

Morphology and mosaics of melanopsin-expressing retinal ganglion cell types in mice Read More »

Role of neurokinin-1 expressing neurons in the locus coeruleus on ventilatory and cardiovascular responses to hypercapnia.

de Carvalho D, Bicego KC, de Castro OW, da Silva GS, Garcia-Cairasco N, Gargaglioni LH (2010) Role of neurokinin-1 expressing neurons in the locus coeruleus on ventilatory and cardiovascular responses to hypercapnia. Respir Physiol Neurobiol 172(1-2):24-31. doi: 10.1016/j.resp.2010.04.016 Summary: NK-1 receptors (NK1R) play an important role in cardiorespiratory responses to hypercapnia. In order to paint

Role of neurokinin-1 expressing neurons in the locus coeruleus on ventilatory and cardiovascular responses to hypercapnia. Read More »

Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons.

Sugiura A, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Norimoto M, Orita S, Eguchi Y, Kuniyoshi K, Ochiai N, Kishida S, Takaso M, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Nakamura J, Takahashi K (2010) Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide

Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons. Read More »

BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons.

Schnitzler AC, Mellott TJ, Lopez-Coviella I, Tallini YN, Kotlikoff MI, Follettie MT, Blusztajn JK (2010) BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons. J Neurosci 30(24):8221-8228. doi: 10.1523/JNEUROSCI.5611-09.2010 PMID: 20554873 Summary: Bone morphogentic protein (BMP) 9 is a cholinergic differentiation factor that increases acetylcholine synthesis

BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons. Read More »

Noradrenergic neurons of the area postrema mediate amylin’s hypophagic action.

Potes CS, Turek VF, Cole RL, Vu C, Roland BL, Roth JD, Riediger T, Lutz TA (2010) Noradrenergic neurons of the area postrema mediate amylin’s hypophagic action. Am J Physiol Regul Integr Comp Physiol 299(2):R623-631. doi: 10.1152/ajpregu.00791.2009 Summary: Amylin decreases food intake in rats and is a satiation signal affecting the area postrema (AP). This

Noradrenergic neurons of the area postrema mediate amylin’s hypophagic action. Read More »

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