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Gene expression profile in rat hippocampus with and without memory deficit.

Paban V, Farioli F, Romier B, Chambon C, Alescio-Lautier B (2010) Gene expression profile in rat hippocampus with and without memory deficit. Neurobiol Learn Mem 94(1):42-56. doi: 10.1016/j.nlm.2010.03.005

Summary: This work examined a wide range of gene expression in the rat hippocampus after bilateral injections of 192-IgG-SAP (Cat. #IT-01) – 37.5 ng per side in the medial septum, and 75 ng per side in the nucleus basalis magnocellularis. Memory loss following 192-IgG-SAP treatment was marked by gene expression that did not show the same cluster organization as learning processes. Genes showing differential expression were down-regulated, and one cluster associated with tissue remodeling could be identified.

Related Products: 192-IgG-SAP (Cat. #IT-01)