Author name: Kristen Hartman

Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin.

Emanuel AJ, Ritter S (2010) Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin. Endocrinology 151(7):3237-3246. doi: 10.1210/en.2010-0219 Summary: In this work the authors investigated the role of hindbrain catecholamine neurons in the response to a gastrointestinal peptide, ghrelin. Rats received 42 ng injections of anti-DBH-SAP (Cat. #IT-03) into the […]

Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin. Read More »

Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion.

Zikri NN, Schumer E, Wang JJ, Gaughan A, Hadley GA, Moffatt-Bruce SD (2010) Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion. J Surg Res 163(1):162-168. doi: 10.1016/j.jss.2010.04.021 Summary: CD8+ T cells expressing CD103 have been shown to play a key role in the rejection of renal allografts. Use of M290-SAP (a custom saporin conjugation)

Induction of CD4(+)CD25(+) T regulatory cells with CD103 depletion. Read More »

Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts.

Coradazzi M, Gulino R, Garozzo S, Leanza G (2010) Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts. J Neurochem 114(3):761-771. doi: 10.1111/j.1471-4159.2010.06800.x Summary: The authors removed noradrenergic neurons in the locus coeruleus/subcoeruleus complex of neonatal rats with 0.25-1.0 µg bilateral injections of anti-DBH-SAP (Cat. #IT-03).

Selective lesion of the developing central noradrenergic system: Short- and long-term effects and reinnervation by noradrenergic-rich tissue grafts. Read More »

Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina.

Gonzalez-Menendez I, Contreras F, Cernuda-Cernuda R, Provencio I, Garcia-Fernandez JM (2010) Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina. Invest Ophthalmol Vis Sci 51(9):4840-4847. doi: 10.1167/iovs.10-5253 PMID: 20435589 Summary: Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) adjust the circadian pacemaker of mammals by detecting light. The authors tracked

Postnatal development and functional adaptations of the melanopsin photoreceptive system in the albino mouse retina. Read More »

Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.

Hovinga KE, Shimizu F, Wang R, Panagiotakos G, Van Der Heijden M, Moayedpardazi H, Correia AS, Soulet D, Major T, Menon J, Tabar V (2010) Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate. Stem Cells 28:1019-1029. doi: 10.1002/stem.429 PMID: 20506127 Summary: The antibody CD105 (1:1,000) was incubated with

Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate. Read More »

Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.

Vincent BG, Young EF, Buntzman AS, Stevens R, Kepler TB, Tisch RM, Frelinger JA, Hess PR (2010) Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice. J Immunol 184(8):4196-4204. doi: 10.4049/jimmunol.0903931 Summary: MHC class I tetramers have been used to identify antigen-specific cells. In this

Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice. Read More »

The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A(5) noradrenergic cell group.

Marques-Lopes J, Pinho D, Albino-Teixeira A, Tavares I (2010) The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A(5) noradrenergic cell group. Brain Res 1325:41-52. doi: 10.1016/j.brainres.2010.02.043 Summary: Injection of angiotensin II into the caudal ventrolateral medulla (CVLM) has been shown to induce angiotensin

The hyperalgesic effects induced by the injection of angiotensin II into the caudal ventrolateral medulla are mediated by the pontine A(5) noradrenergic cell group. Read More »

Cardiovascular and behavioural responses to conditioned fear and restraint are not affected by retrograde lesions of A5 and C1 bulbospinal neurons.

Vianna DM, Carrive P (2010) Cardiovascular and behavioural responses to conditioned fear and restraint are not affected by retrograde lesions of A5 and C1 bulbospinal neurons. Neuroscience 166:1210-1218. doi: 10.1016/j.neuroscience.2010.01.039 Summary: To investigate the role of A5 neurons in some forms of psychological stress the authors injected 22 or 44 ng of anti-DBH-SAP (Cat. #IT-03)

Cardiovascular and behavioural responses to conditioned fear and restraint are not affected by retrograde lesions of A5 and C1 bulbospinal neurons. Read More »

The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies

Klinkenberg I, Blokland A (2010) The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies. Neurosci Biobehav Rev 34(8):1307-1350. doi: 10.1016/j.neubiorev.2010.04.001 PMID: 20398692 Objective: To provide an overview is given of the effects of scopolamine on animal behavior. Summary: The most important and influential articles over the past

The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies Read More »

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