Advanced Targeting Systems continues to search for funding to develop Substance P-Saporin (SP-SAP) as a chronic pain therapeutic. In May of last year we decided to seek venture capital funding and began traveling to make presentations to potential investors. The response from most everyone we spoke to was positive and they thought the potential of […]
SP-SAP as a Chronic Pain Therapeutic: An Update Read More »
Contributed by William Truitt, PhD, Department of Cell Biology, Neurobiology, and Anatomy, Neuroscience Graduate Program, University of Cincinnati, College of Medicine, Post Office Box 670521, Cincinnati, OH 45267-0521, USA. Previously we demonstrated the existence of a spinothalamic pathway in the male rat where neural activation is specifically induced by ejaculation.1 This pathway includes the parvocellular
Cover Article: Deep Lumbar Neurons Control Ejaculation Read More »
Read the 2002 Newsletters and receint scientific references 2002, issue 1: Control Conjugates: The Perfect Companion for Targeted Toxins / by Lappi DA / featuring Control Conjugates SFN Poster of the Year Targeting Talk: Toxin Safety Targeting Tools: Serotonin Transporter Antibody 2002, issue 2: HCRT-SAP Lesion Produces Sleepiness While anti-DBH-SAP Lesion Does Not / by Blanco-Centurion
Targeting Trends 2002 Newsletter Read More »
Awarded by ATS at Society for Neuroscience (SFN) Orlando, FL • November 3-6, 2002 Be sure to check out the cover article in our Targeting Trends newsletter (First Quarter, 2003). 69.2 LESIONS OF SPINOTHALAMIC NEURONS IN LUMBAR SPINAL CORD DISRUPT EJACULATORY REFLEXES IN MALE RATS. WA Truitt; KE McKenna; LM Coolen featuring IT-11 SSP-SAP (Poster)
SFN Poster of the Year 2002 Read More »
Contributed by Jean-Christophe Cassel, PhD, Laboratoire de Neurosciences Cognitives et Comportementales, UMR 7521 Université Louis Pasteur/CNRS, Strasbourg, France & Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität Freiburg, Neuropharmakologisches Labor, Freiburg, Germany. Dr. Cassel and colleagues are the authors of four publications released this quarter using 192-Saporin (Cat. #IT-01) Trying to understand how
Cover Article: Does 192-IgG-Saporin or 5,7-DHT kill cognitive functions in the rat? Read More »
Advanced Targeting Systems announces the release of two reagents for immunological studies: Anti-Tac (Cat. # AB-18) – a monoclonal antibody to human CD25, the interleukin-2 receptor, and Anti-Tac-SAP (Cat. # IT-24) – the immunotoxin made by conjugation of anti-Tac to saporin. These reagents add to the growing list of ATS products for use in studies
Targeting Tools: Anti-Tac and Anti-Tac-SAP Read More »
Contributed by David J Flavell, PhD, The Simon Flavell Leukaemia Research Unit, Division of Cancer Sciences, University of Southampton Medical School, United Kingdom. I have asked Dr. Flavell to contribute an article on the clinical use of his saporin immunotoxins. Dr. Flavell’s research unit is named after his son, who died from leukemia. At that
Cover Article: Saporin Immunotoxins for Treating Human Hematological Malignancies Read More »