FGF-2, or basic fibroblast growth factor, binds all of the FGF receptors with high affinity. We have used this molecule to produce FGF-SAP (Cat. #IT-38), which has a healthy experimental publication record (“FGF” and “saporin” in PubMed: 25 hits). It has been used to clean primary cultures of fibroblasts.[1] It was important in determining the

Species Reactivity: Human, Rat, Mouse, Rabbit Anti-AChR (Cat. #AB-N36) binds with high affinity to the AChR subtype with 59 kDa ACh-binding subunits, but with considerably lower affinity to the AChR subtype with 75 kDa subunits. Anti-AChR binds to the main immunogenic region on α1 subunits of muscle-type AChRs. Reference 1. Schoepfer R, Halvorsen SW, Conroy

SP-CTA (Cat. #IT-39) is an exciting new tool for use in the research of neurokinin (NK-1) receptor-expressing cells of the central nervous system. A conjugate of the substance P molecule and the catalytic subunit of Cholera toxin, this product can be used very effectively in vivo for increasing sensitization of these neuronal cells. Selectively targeting

What is the claustrum? The simple answer is that it’s a brain structure that lies under the insular and piriform cortices. What it does is rather unclear, but one hypothesis has drawn considerable attention. The claustrum contains projections to the entire cortex, and this may indicate that it plays an important role in brain function.