Annual Molecular Pathobiology Innovative Research Symposium

Advanced Targeting Systems Silver Sponsor Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Topics Bone integrity Fibronectin Mast cells Neuropathic pain Oral cancer Pain Stem Cells Teeth TRPV1   Products Anti-NK1R Anti-SERT-SAP Bombesin-SAP […]

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Targeted Toxins for Neuroscience

Targeted Toxins for Neuroscience Antibody Screening for Neuroscience There is a growing need for therapeutics for cancer, autoimmune diseases, blood diseases and Alzheimer’s disease. Due to their ability to bind to a specific target antigen, monoclonal antibodies are increasingly being screened for therapeutic drug development. In May 2021, the FDA approved the 100th monoclonal antibody

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Saporin Uses in Immunology

One of the more common methods of using Streptavidin-ZAP is to couple the complex with biotinylated antibodies. However, there are also many instances of biotinylated ligands, peptides, and even biotinylated major histocompatibility complex (MHC) tetramers in immunology fields. B-Cell Targeting. An example of utilizing Streptavidin-ZAP to study ligands that target CD22 were shown by Collins

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Immunology

NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07) The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective

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American Association of Immunologists, AAI 2023

May 12-14, Booth 5067 Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 5067, May 12-14 and find out how you can use Molecular Surgery. Curated Resources Saporin Uses in Immunology Immunology

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Animal Models

ATS Animal Models ATS offers many different Animal Model products and full kits for various disease and behavioral research applications. Animal Models Learn more about our Saporin-produced Animal Models. Choose the product links below for the Animal Model of your interest. Most Animal Models are ready in 2 weeks using our Saporin conjugate system to

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Toolbox: pHast Conjugates

pHast Conjugates pHast Conjugates are one of our pHastest tools for quantitative testing of your primary antibody’s specificity, binding, and internalization, providing results in 1 day. How It Works The pHast conjugate binds to your primary antibody via a secondary antibody cross-linked to a pH-dependent fluorescent reporter.  This fluorescent reporter will increase intensity as the

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