Targeting Topics

Your back-up laboratory team is here

Assay and Conjugation Services Restricted access can slow or halt your research and drug development activities.  We can help!  Here is just one of the services CytoLogistics provides to research and drug development laboratories around the world.    Cell Transfections Transfections can be a time-consuming and tedious process.  Let CytoLogistics help you with the experimental …

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Tools and Services to Advance your Research and Drug Development

TOOLS FOR SELECTIVELY ALTERING CELLS BASED ON CELL-SURFACE MARKERS You’re still publishing and we’re still open to meet your targeting needs.  You can place your orders online or contact us. Stay safe and healthy!Denise Higginswww.ATSbio.com SERVICES FOR SELECTIVELY ALTERING AND ASSAYING CELLS Restricted access can slow or halt your research and drug development activities.  We …

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Recent Publications using ATS Products

Borkowski LF, & Nichols NL. A2A and 5-HT Receptors are Differentially Required for Respiratory Plasticity Over the Course of Motor Neuron Loss in Intrapleurally CTB-SAP Treated Rats. (2019). FASEB J, 33 (1_supplement):843.843-843.843. IT-14: CTB-SAP Dose: Bilateral, intrapleural injections of: 1) CTB-SAP (25 μg), or 2) un-conjugated CTB and SAP (control) in rats. Toledo C, Andrade …

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Research Tools for Parkinson’s Disease

A review of the tools for studying Parkinson’s Disease These results show that an antibody to the extracellular domain of the dopamine transporter (DAT) can be used to target midbrain dopaminergic neurons and that Anti-DAT-Saporin may be useful for producing a lesion very similar to the naturally-occurring neural degeneration seen in Parkinson’s Disease (Wiley et …

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Alzheimer’s Disease models

A review of the tools for creating animal models of Alzheimer’s Disease “192 IgG-saporin binds selectively and irreversibly to low-affinity nerve growth factor receptor interrupting cholinergic neuronal protein synthesis.” “Anti-DBH-SAP allows a selective and gradual lesioning of noradrenergic neurones in the brain stem nucleus locus coeruleus, the primary site of noradrenaline production in the CNS.” …

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Award winner for animal model of temporal lobe epilepsy

Congratulations to Dr. Argyle Bumanglag and the team at University of Florida for the important work they presented using SSP-SAP to create an animal model of temporal lobe epilepsy. Injections of SSP-SAP into the hippocampus of a rat causes acute hippocampal injury, permanent dentate granule cell-onset epilepsy, and hippocampal sclerosis that closely resembles the selective …

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SfN Poster of the Year Contenders

The Society for Neuroscience meeting is just around the corner.  Come visit us in Chicago  – October 19-23, Booth #763.  Here is a list of the posters competing for the Annual Post of the Year Award using ATS products. (click to zoom) Saturday, October 19 Sunday, October 20 Monday, October 21 Tuesday, October 22 Wednesday, …

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Fab-pHast products

Fab-pHast products bind to your primary antibody via a secondary antibody or Streptavidin cross-linked to a pH-dependent fluorescent reporter.  This fluorescent reporter increases intensity as the pH of its surroundings becomes more acidic, as evident when exposed to the environment inside a cell. SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked …

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