Author name: Kristen Hartman

0054 SUVN-G3031, a histamine H3 receptor inverse agonist produces wake promoting effect in orexin-2-saporin lesioned rats.

Benade V, Daripelli S, Tirumalasetty C, Subramanian R, Petlu S, Badange R, Nirogi R (2019) 0054 SUVN-G3031, a histamine H3 receptor inverse agonist produces wake promoting effect in orexin-2-saporin lesioned rats. Sleep 42(Supplement_1):A22-A23. doi: 10.1093/sleep/zsz067.053 Summary: Rats lesioned with Orexin-SAP in lateral hypothalamus produced narcoleptic-like behavior. Related Products: Orexin-B-SAP (Cat. #IT-20)

0054 SUVN-G3031, a histamine H3 receptor inverse agonist produces wake promoting effect in orexin-2-saporin lesioned rats. Read More »

Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons.

Deura C, Minabe S, Ikegami K, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H (2019) Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons. J Reprod Dev 65(2):129-137. doi: 10.1262/jrd.2018-122 Objective: To examine the existence of a neuronal pathway from the hindbrain ependymocytes to kisspeptin neurons in the arcuate nucleus

Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons. Read More »

Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex.

Urquhart MA, Ross JA, Reyes BAS, Nitikman M, Thomas SA, Mackie K, Van Bockstaele EJ (2019) Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex. Neurobiology of Stress 10:100164. doi: 10.1016/j.ynstr.2019.100164 Objective: To determine the effects of NE depletion on the eCB system. Summary: The results suggest that the

Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex. Read More »

Call for Proposals

Advanced Targeting Systems and its Contract Service partner, CytoLogistics announce a Call For Proposals for research collaborations on: Receptor-mediated Delivery: New Targets Selected researchers will receive support for smaller scale or pilot research projects ($1,000 – $25,000) with the targeting tools and contract services needed for the identification and characterization of new cell-surface markers for

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Targeting Tools: Top Twenty of 2018

Top Five Targeted Toxins 1. CTB-SAP (Cholera Toxin B-Saporin) (Cat. #IT-14) – targets cells expressing GM1 receptor 2. Anti-DBH-SAP (Cat. #IT-03) – targets cells expressing rat dopamine beta-hydroxylase (DBH) 3. 192-IgG-SAP (192-Saporin) (Cat. #IT-01) – targets cells expressing rat p75NTR 4. Anti-ChAT-SAP (Cat. #IT-42) – targets cells expressing choline acetyltransferase 5. Nppb-SAP (Neuropeptide natriuretic polypeptide

Targeting Tools: Top Twenty of 2018 Read More »

2018 Poster of the Year

Nilupaer Abudukeyoumu! Her poster was presented at the 2018 Society for Neuroscience meeting that was held in San Diego, CA: Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons Authors on the winning poster are pictured below L. to R.: Nilupaer Abudukeyoumu, Marianela Garcia-Munoz, Yoko Nakano, and Gordon W. Arbuthnott. Nilupaer Abudukeyoumu is a

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Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons

by Nilupaer Abudukeyoumu, Marianela Garcia-Munoz, Yoko Nakano, Gordon W. Arbuthnott.Brain Mechanism for Behavior Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan Cholinergic interneurons (ChIs) are sparsely distributed within the striatum, a nucleus that plays important roles in voluntary motor control, associated learning, procedural memory, execution of movement, action selection, and planning.[1] ChIs

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Targeting Trends 2018 Review

Read the complete 2018 Review and recent Scientific References Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons. / by N Abudukeyoumu et al. / featuring Anti-ChAT-SAP, Cat. #IT-42 2018 Poster of the Year Award Product Managers Targeting Tools: Top Twenty of 2018 Call For Proposals for research collaborations on Receptor-mediated Delivery: New Targets

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Featured Article: Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons

Abudukeyoumu N, Garcia-Munoz M, Nakano Y, Arbuthnott GW (2018) Featured Article: Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons. Targeting Trends 19 Related Products: Anti-ChAT-SAP (Cat. #IT-42) Read the featured article in Targeting Trends. See Also: Abudukeyoumu N et al. Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons. Neuroscience 2018 Abstracts

Featured Article: Impaired reach-to-grasp responses in mice depleted of striatal cholinergic interneurons Read More »

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