Author name: Kristen Hartman

Dorso-ventral heterogeneity in tracheal basal stem cells

Tadokoro T, Tanaka K, Osakabe S, Kato M, Kobayashi H, Hogan BLM, Taniguchi H (2021) Dorso-ventral heterogeneity in tracheal basal stem cells. Biol Open 10(9):bio058676. doi: 10.1242/bio.058676 PMID: 34396394 Objective: To determine whether tracheal basal cells (BCs) from the dorso-ventral airways have intrinsic molecular and behavioural differences relevant to their in vivo function. Summary: This […]

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The biology of hematopoietic stem cells and its clinical implications

Skulimowska I, Sosniak J, Gonka M, Szade A, Jozkowicz A, Szade K (2021) The biology of hematopoietic stem cells and its clinical implications. FEBS J 16192. doi: 10.1111/febs.16192 Objective: To review the opportunities and challenges of recent findings to improve the clinical use of hematopoietic stem cells (HSCs) Summary: The authors describe new methods of

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Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease

Barrett MJ, Murphy JM, Zhang J, Blair JC, Flanigan JL, Nawaz H, Dalrymple WA, Sperling SA, Patrie J, Druzgal TJ (2021) Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease. Parkinsonism Relat Disord 90:27-32. doi: 10.1016/j.parkreldis.2021.07.024 Summary: This study examined the relationship between olfaction, longitudinal change in cholinergic basal forebrain nuclei and their

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Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats

Duggan MR, Joshi S, Strupp J, Parikh V (2021) Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats. Brain Struct Funct 226(7):2357-2373. doi: 10.1007/s00429-021-02336-2 Objective: To test the hypothesis that reduced PFC output would exert differential effects on attentional capacities in young and aged rats, with the

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Neural circuitry underlying REM sleep: A review of the literature and current concepts

Wang YQ, Liu WY, Li L, Qu WM, Huang ZL (2021) Neural circuitry underlying REM sleep: A review of the literature and current concepts. Prog Neurobiol 204:102106. doi: 10.1016/j.pneurobio.2021.102106 Summary: To investigate the role of the LC in sleep the authors injected 0.3 µl of 192-Saporin (Cat. IT-01) or anti-DBH-SAP (Cat. #IT-03) at 1 µg/µl.

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Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory

Soma S, Suematsu N, Sato AY, Tsunoda K, Bramian A, Reddy A, Takabatake K, Karube F, Fujiyama F, Shimegi S (2021) Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory. Neurobiol Learn Mem 183:107484. doi: 10.1016/j.nlm.2021.107484 Summary: The authors tested the effect of a cholinesterase inhibitor, donepezil, on the retrieval of memory

Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory Read More »

Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections

Borkowski LF, Smith CL, Keilholz AN, Nichols NL (2021) Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections. J Neurophysiol 126(3):709-722. doi: 10.1152/jn.00236.2021 Objective: The authors tested the hypothesis that phrenic long-term facilitation (pLTF) following treatment with CTB-SAP is: 1) adenosine 2A (A2A) receptor-dependent

Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections Read More »

Cholinergic modulation of sensory processing in awake mouse cortex

Jimenez-Martin J, Potapov D, Potapov K, Knöpfel T, Empson RM (2021) Cholinergic modulation of sensory processing in awake mouse cortex. Sci Rep 11(1):17525. doi: 10.1038/s41598-021-96696-8 Objective: To decipher the timing and significance of acetylcholine actions. Summary: Study provides new insights into how the cortex processes sensory information and how loss of acetylcholine, for example in

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Roles of the FGF-FGFR signaling system in cancer development and inflammation

Wiedlocha A, Haugsten EM, Zakrzewska M (2021) Roles of the FGF-FGFR signaling system in cancer development and inflammation. Cells 10(9):2231. doi: 10.3390/cells10092231 PMID: 34571880 Objective: To highlight the latest advances in understanding the role of the FGF-FGFR signaling system in the development of neoplastic diseases and in the induction and maintenance of inflammation and its

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