Visit ATS April 7-10, Booth 3453 to discover how ATS products can advance your Cancer Research Antibody Drug Conjugates to Treat Cancer A Brief History of Saporin and its Contributions to Neuroscience Targeted Toxins – Cheaper and Quicker than Knockouts A rapid, pH-sensitive screening method to detect internalization of cell surface markers for development of […]
American Association for Cancer Research, AACR 2024 Read More »
Antibody Drug Conjugates to Treat Cancer Antibody Screening for Cancer Research and Drug Development There is a growing need for therapeutics for cancer, autoimmune diseases, blood diseases and Alzheimer’s disease. Due to their ability to bind to a specific target antigen, monoclonal antibodies are increasingly being screened for therapeutic drug development. In May 2021, the
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Nord C, Jones I, Garcia-Maestre M, Hägglund AC, Carlsson L (2024) Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn 253(10):922-939. doi: 10.1002/dvdy.707 PMID: 38546215 Objective: To demonstrate that mTORC1 mediates critical roles during neuronal lamination using the mouse retina as a model system. Summary: This study establishes a critical role for
Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits Read More »
Huang M, Fang W, Farrel A, Li L, Chronopoulos A, Nasholm N, Cheng B, Zheng T, Yoda H, Barata MJ, Porras T, Miller ML, Zhen Q, Ghiglieri L, McHenry L, Wang L, Asgharzadeh S, Park J, Gustafson WC, Matthay KK, Maris JM, Weiss WA (2024) ALK upregulates POSTN and WNT signaling to drive neuroblastoma. Cell
ALK upregulates POSTN and WNT signaling to drive neuroblastoma Read More »
Nattkemper LA, Kim BS, Yap QV, Hoon MA, Mishra SK, Yosipovitch G (2024) Increased systemic levels of centrally acting b-type natriuretic peptide are associated with chronic itch of different types. J Invest Dermatol S0022-202X(24)00197-0. doi: 10.1016/j.jid.2024.02.026 PMID: 38522572 Objective: Examines plasma BNP levels and N-terminal pro-BNP levels in patients with differing types of chronic itch
Huang L, Zhu W, Li N, Zhang B, Dai W, Li S, Xu H (2024) Functions and mechanisms of adenosine and its receptors in sleep regulation. Sleep Med 115:210-217. doi: 10.1016/j.sleep.2024.02.012 PMID: 38373361 Objective: To summarize the current research on the functions and possible mechanisms of adenosine and its receptors in regulating sleep and homeostatic
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Décarie-Spain L, Hayes AMR, Lauer LT, Kanoski SE (2024) The gut-brain axis and cognitive control: A role for the vagus nerve. Semin Cell Dev Biol 156:201-209. doi: 10.1016/j.semcdb.2023.02.004 PMID: 36803834 Objective: To review evidence from rodent and human studies on how gastrointestinal vagus nerve signaling influences higher-order neurocognitive processes such as anxiety, motivation, learning, and
The gut-brain axis and cognitive control: A role for the vagus nerve Read More »
Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish Leonardo Ancheta, Vice President and Director of Custom Conjugations at ATS, talks about how to make experiments more efficient and more accurate and also lower your costs. keywords: custom conjugation, custom conjugate, custom services, secondary conjugate, direct
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Moreno-Rodríguez M, Martínez-Gardeazabal J, Bengoetxea de Tena I, Llorente-Ovejero A, Lombardero L, González de San Román E, Giménez-Llort L, Manuel I, Rodríguez-Puertas R (2024) Cortical lipids containing choline mediate cannabinoid-induced cognitive improvement. bioRxiv 2024.03.07.583670. doi: 10.1101/2024.03.07.583670 Objective: Investigate the neuroprotective effect of treatment with the CB1 cannabinoid agonist, WIN55,212-2, against cholinergic degeneration. Summary: The endocannabinoid
Cortical lipids containing choline mediate cannabinoid-induced cognitive improvement Read More »
Qian C, Xin Y, Qi C, Wang H, Dong BC, Zack DJ, Blackshaw S, Hattar S, Zhou FQ, Qian J (2024) Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells. Nat Commun 15(1):2206. doi: 10.1038/s41467-024-46428-z PMID: 38467611 Objective: To explore how intercellular communication contributes to retinal ganglion cell (RGC) survival following