by Kristen Ashley Horner and collaborators R. Murray and M.C. LoganMercer University School of Medicine, Savannah, GA 31404 Repeated exposure to psychostimulants, such as cocaine, can result in patterns of repetitive, inflexible behaviors, known as stereotypy.[1,2] These inflexible behaviors are thought to be similar to the type of behaviors observed with certain psychiatric disorders, such […]
Xia W, Liu Y (2016) Targeted ablation of cardiac sympathetic neurons: A promising approach to prevent sudden cardiac death. Int J Cardiol 202:425-426. doi: 10.1016/j.ijcard.2015.09.049 Summary: Sudden cardiac death (SCD) refers to an unexpected death due to cardiovascular causes, occurring generally within 1 hr of symptom onset, in a person without any prior condition that
Read the 2015 Newsletters and recent scientific references 2015, issue 1: Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in Parkinson’s Disease / by Aaron Kucinski / featuring 192-IgG-SAP (Cat. #IT-01), Anti-ChAT-SAP (Cat. #IT-42) Society for Neuroscience Poster of the Year Award Veterinary Development of Substance P-Saporin (SP-SAP) Targeting Talk:
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Humana Press has released its newest offer to the Neuroscience community, Molecular Neurosurgery With Targeted Toxins, with Ronald G. Wiley and Douglas A. Lappi as editors. This book contains articles by “the best and the brightest” who have used targeted toxins for probing difficult in vivo systems biology issues. To order — please contact ATS
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Petrosini L, De Bartolo P, Cutuli D, Gelfo F (2016) Perinatal 192 IgG-saporin as neuroteratogen. Curr Top Behav Neurosci 29:111-123. doi: 10.1007/7854_2015_418 Summary: The authors discuss the effects of perinatal administration of 192-IgG-SAP (Cat. #IT-01) and areas of research that have been investigated through the use of these lesions. The chapter covers a description of
Perinatal 192 IgG-saporin as neuroteratogen. Read More »
McCabe KL, Kunzevitzky NJ, Chiswell BP, Xia X, Goldberg JL, Lanza R (2015) Efficient generation of human embryonic stem cell-derived corneal endothelial cells by directed differentiation. PLoS One 10(12):e0145266. doi: 10.1371/journal.pone.0145266 PMID: 26689688 Usage: For immunostaining of the expression of Zona Occludens protein 1 (ZO-1), von Willebrand factor (vWF), p75/NGFR and CD31, traditional methods were
Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish keywords: biotinylated molecules, screen, Biotin-Z Internalization kit, binding, internalization, targeting agent, cell surface marker, saporin, custom, streptavidin, Streptavidin-ZAP, secondary
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Also available in Japanese | German | French | Korean | Mandarin | Italian | Spanish A description of the components in an Antibody Internalization Kit by Advanced Targeting Systems. This kit is used to screen antibodies for their specificity and ability to internalize. The technology uses a secondary antibody conjugated to saporin. Simply mix
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Lai BQ, Qiu XC, Zhang K, Zhang RY, Jin H, Li G, Shen HY, Wu JL, Ling EA, Zeng YS (2015) Cholera toxin b subunit shows transneuronal tracing after injection in an injured sciatic nerve. PLoS One 10(12):e0144030. doi: 10.1371/journal.pone.0144030 PMID: 26640949 Related Products: Cholera Toxin B, Recombinant (Cat. #PR-14)
Congratulations to this year’s winner of ATS’ Poster of the Year featuring Dermorphin-SAP (Cat. #IT-12). Horner KA, Logan M, Murray RC (2015) Ablation of the patch compartment reduces cocaine-induced stereotypy. Neuroscience 2015 Abstracts 506.23/M12. Society for Neuroscience, Chicago IL Be sure to check out the featured article in Targeting Trends. Repeated exposure to cocaine (COC) induces
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