Author name: Kristen Hartman

Cholinergic modulation targeting medial prefrontal cortex leads to behavior deficit in interval timing task

Zhang Q, De Corte B, Jung D, Kim Y, Geerling J, Narayanan N (2018) Cholinergic modulation targeting medial prefrontal cortex leads to behavior deficit in interval timing task. Neurology 90 (15 Supplement):P5.195. Objective: To determine the effect of cholinergic lesion targeting medial prefrontal cortex on interval timing behavior. Summary: Mice receiving medial prefrontal mu-p75-saporin injection […]

Cholinergic modulation targeting medial prefrontal cortex leads to behavior deficit in interval timing task Read More »

Early CALP2 expression and microglial activation are potential inducers of spinal IL-6 upregulation and bilateral pain following motor nerve injury

Chen SX, Wang SK, Yao PW, Liao GJ, Na XD, Li YY, Zeng WA, Liu XG, Zang Y (2018) Early CALP2 expression and microglial activation are potential inducers of spinal IL-6 upregulation and bilateral pain following motor nerve injury. J Neurochem 145:154-169. doi: 10.1111/jnc.14317 Related Products: Mac-1-SAP rat (Cat. #IT-33)

Early CALP2 expression and microglial activation are potential inducers of spinal IL-6 upregulation and bilateral pain following motor nerve injury Read More »

The combinational use of CRISPR/Cas9 and targeted toxin technology enables efficient isolation of bi-allelic knockout non-human mammalian clones

Watanabe S, Sakurai T, Nakamura S, Miyoshi K, Sato M (2018) The combinational use of CRISPR/Cas9 and targeted toxin technology enables efficient isolation of bi-allelic knockout non-human mammalian clones. Int J Mol Sci 19:E1075. doi: 10.3390/ijms19041075 Objective: Most genome editing systems employ transient treatment with selective drugs such as puromycin to obtain the desired genome-edited

The combinational use of CRISPR/Cas9 and targeted toxin technology enables efficient isolation of bi-allelic knockout non-human mammalian clones Read More »

Detection of oxidative stress in buccal cells using iSWAB tubes

Bassil M, Atat AA, Ibragim M (2018) Detection of oxidative stress in buccal cells using iSWAB tubes. J Mol Biomark Diagn 9(2):1-6. doi: 10.4172/2155-9929.1000387 PMID: 909090 Objective: To investigate the oxidative profile of iSWAB-Mawi protein tubes by examining their ability to detect the protein oxidation biomarkers: nitrotyrosine and S-nitrosocysteine in buccal cells. Summary: Results showed

Detection of oxidative stress in buccal cells using iSWAB tubes Read More »

The establishment of a CSF-contacting nucleus “knockout” model animal.

Song SY, Zhang LC (2018) The establishment of a CSF-contacting nucleus “knockout” model animal. Front Neuroanat 12:22. doi: 10.3389/fnana.2018.00022 Objective: To establish a cerebrospinal fluid (CSF)-contacting nucleus-deficient model animal using cholera toxin B subunit-saporin (CTB-SAP). Summary: The complete ablation occurred by Day 7 after CTB-SAP microinjection. A model animal that had no CSF-contacting nucleus was

The establishment of a CSF-contacting nucleus “knockout” model animal. Read More »

Brainstem catecholaminergic neurones and breathing control during postnatal development in male and female rats.

Patrone LGA, Biancardi V, Marques DA, Bícego KC, Gargaglioni LH (2018) Brainstem catecholaminergic neurones and breathing control during postnatal development in male and female rats. J Physiol 596(15):3299-3325. doi: 10.1113/JP275731 Objective: To determine the role of the brainstem CA system in ventilatory control under normocapnic and hypercapnic conditions during different phases of development (P7-8, P14-15

Brainstem catecholaminergic neurones and breathing control during postnatal development in male and female rats. Read More »

Real‐time electrochemical monitoring of choline during systemic inflammation in the freely‐ moving mouse

Doyle S, Baker KL, Cunningham C, Lowry JP (2018) Real‐time electrochemical monitoring of choline during systemic inflammation in the freely‐ moving mouse. Monitoring Molecules in Neuroscience . 17th International Conference, Oxford, UK Summary: The loss of cholinergic innervation (mu p75‐SAP lesion in the basal forebrain) abolished the scopolamine‐induced choline increase in the hippocampus. Related Products:

Real‐time electrochemical monitoring of choline during systemic inflammation in the freely‐ moving mouse Read More »

Effect of chronic intermittent hypoxia on angiotensin II receptors in the central nervous system

Morgan BJ, Schrimpf N, Rothman M, Mitzey A, Brownfield MS, Speth RC, Dopp JM (2018) Effect of chronic intermittent hypoxia on angiotensin II receptors in the central nervous system. Clin Exp Hypertens 41:1-7. doi: 10.1080/10641963.2018.1451536 PMID: 29561178 Objective: To quantify the effects of chronic intermittent hypoxia (CIH) on AT1R- and AT2R-like immunoreactivity in the rostroventrolateral

Effect of chronic intermittent hypoxia on angiotensin II receptors in the central nervous system Read More »

Differential roles for cryptochromes in the mammalian retinal clock

Wong JCY, Smyllie NJ, Banks GT, Pothecary CA, Barnard AR, Maywood ES, Jagannath A, Hughes S, van der Horst GTJ, MacLaren RE, Hankins MW, Hastings MH, Nolan PM, Foster RG, Peirson SN (2018) Differential roles for cryptochromes in the mammalian retinal clock. FASEB J 32:4302-4314. doi: 10.1096/fj.201701165RR PMID: 29561690 Objective: To determine roles of cryptochromes

Differential roles for cryptochromes in the mammalian retinal clock Read More »

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